About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Nr1h2
nuclear receptor subfamily 1, group H, member 2
MGI:1352463
60 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Npc1m1N/Npc1m1N
Nr1h2tm1Djm/Nr1h2tm1Djm
involves: 129S6/SvEvTac * BALB/c 		premature death J:130969
Nr1h2tm1.1Gstr/Nr1h2+
Rxrbtm1Mma/Rxrb+
involves: 129 * C57BL/6 		abnormal Sertoli cell morphology J:101966
Nr1h2tm1.1Gstr/Nr1h2tm1.1Gstr
Nr1h3tm1.1Gstr/Nr1h3tm1.1Gstr
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal alveolar lamellar body morphology J:234268
abnormal astrocyte morphology J:81790
abnormal brain ependyma morphology J:81790
abnormal brain vasculature morphology J:81790
abnormal brain ventricle morphology J:81790
abnormal cerebral aqueduct morphology J:81790
abnormal cholesterol homeostasis J:81790
abnormal choroid plexus morphology J:81790
abnormal lateral ventricle morphology J:81790
abnormal lipid homeostasis J:81790
abnormal lipid level J:234268
abnormal lung morphology J:234268
abnormal myelin sheath morphology J:81790
abnormal myelination J:81790
abnormal neurohypophysis median eminence morphology J:81790
abnormal pulmonary alveolar parenchyma morphology J:234268
abnormal pulmonary alveolar system morphology J:234268
abnormal spinal cord central canal morphology J:81790
abnormal substantia nigra pars reticulata morphology J:81790
abnormal third ventricle morphology J:81790
absent choroid plexus J:81790
astrocytosis J:81790
decreased neuron number J:81790
increased lung squamous cell carcinoma incidence J:234268
increased macrophage derived foam cell number J:81790, J:234268
intracranial hemorrhage J:81790
lung inflammation J:234268
neuron degeneration J:81790
premature death J:234268
respiratory distress J:234268
small fourth ventricle J:81790
small lateral ventricles J:81790
small third ventricle J:81790
Nr1h2tm1Djm/Nr1h2tm1Djm
Nr1h3tm1Djm/Nr1h3tm1Djm
involves: 129S6/SvEvTac 		increased liver cholesterol level J:64343
Nr1h2tm1Djm/Nr1h2tm1Djm
Nr1h3tm1Djm/Nr1h3tm1Djm
involves: 129S6/SvEvTac * C57BL/6 		abnormal bone marrow cell physiology J:125452
abnormal female reproductive system morphology J:120923
abnormal female reproductive system physiology J:120923
abnormal macrophage morphology J:125452
abnormal male reproductive system morphology J:120923
abnormal male reproductive system physiology J:120923
abnormal myometrium morphology J:120923
abnormal parturition J:120923
abnormal seminiferous tubule morphology J:120913
abnormal Sertoli cell morphology J:120913
abnormal spermatogonia proliferation J:120913
abnormal uterus physiology J:120923
decreased circulating luteinizing hormone level J:120913
decreased circulating testosterone level J:120913
decreased testis weight J:120913
hindlimb paralysis J:120923
impaired smooth muscle contractility J:120923
increased male germ cell apoptosis J:120913
increased susceptibility to bacterial infection J:81696
increased susceptibility to induced morbidity/mortality J:81696
Leydig cell hypertrophy J:120913
pregnancy-related premature death J:120923
reduced male fertility J:120913
seminiferous tubule degeneration J:120913
testicular atrophy J:120913
Nr1h2tm1Djm/Nr1h2tm1Djm
Tg(APPswe,PSEN1dE9)85Dbo/0
involves: 129S6/SvEvTac * C3H * C57BL/6 		amyloid beta deposits J:122372
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory