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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Abcc9
ATP-binding cassette, sub-family C member 9
MGI:1352630
50 phenotypes from 6 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Abcc9em1(IMPC)H/Abcc9+
C57BL/6N-Abcc9em1(IMPC)H/H 		decreased lymphocyte cell number J:211773
increased grip strength J:211773
increased neutrophil cell number J:211773
Abcc9em1Nich/Abcc9+
involves: C57BL/6J * CBA/J 		abnormal blood vessel physiology J:281903
abnormal channel response J:281903
abnormal heart echocardiography feature J:281903
abnormal thoracic aorta morphology J:281903
abnormal vascular smooth muscle physiology J:281903
aortic arch dilation J:281903
cardiac hypertrophy J:281903
decreased survivor rate J:281903
dilated heart left ventricle J:281903
enlarged heart J:281903
hypotension J:281903
increased cardiac output J:281903
increased cardiac stroke volume J:281903
increased heart weight J:281903
increased vasodilation J:281903
premature death J:281903
Abcc9em1Nich/Abcc9em1Nich
involves: C57BL/6J * CBA/J 		abnormal channel response J:281903
abnormal heart echocardiography feature J:281903
abnormal vascular smooth muscle physiology J:281903
aortic valve regurgitation J:281903
cardiac hypertrophy J:281903
decreased survivor rate J:281903
dilated heart left ventricle J:281903
enlarged heart J:281903
hypotension J:281903
increased cardiac output J:281903
increased cardiac stroke volume J:281903
increased heart weight J:281903
premature death J:281903
Abcc9em2Nich/Abcc9em2Nich
involves: C57BL/6J * CBA/J 		abnormal channel response J:281630
abnormal heart echocardiography feature J:281630
normal behavior/neurological phenotype J:281630
decreased heart left ventricle muscle contractility J:281630
dilated heart left ventricle J:281630
increased muscle fatigability J:281630
increased systemic arterial blood pressure J:281630
Abcc9em3Nich/Abcc9+
B6.Cg-Abcc9em3Nich 		abnormal myocardial fiber currents J:308986
abnormal myocardial fiber morphology J:308986
normal cardiovascular system phenotype J:308986
dilated aorta J:308986
dilated heart J:308986
enlarged heart J:308986
Abcc9em3Nich/Abcc9em3Nich
B6.Cg-Abcc9em3Nich 		abnormal aorta smooth muscle morphology J:308986
abnormal impulse conducting system conduction J:308986
abnormal myocardial fiber currents J:308986
abnormal myocardial fiber morphology J:308986
abnormal physiological response to xenobiotic J:308986
normal cardiovascular system phenotype J:308986
dilated aorta J:308986
dilated heart J:308986
enlarged heart J:308986
Abcc9tm1.1Mcn/Abcc9tm1.1Mcn
Tg(Tagln-cre)1Her/0
involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal fetal cardiomyocyte morphology J:216539
abnormal fetal cardiomyocyte physiology J:216539
abnormal mitochondrial physiology J:216539
abnormal myocardial fiber mitochondrial morphology J:216539
cardiomyopathy J:216539
decreased cardiac muscle contractility J:216539
decreased fatty acid oxidation J:216539
decreased mitochondrial size J:216539
decreased oxygen consumption J:216539
enlarged heart J:216539
normal homeostasis/metabolism phenotype J:216539
hypoxia J:216539
increased cellular sensitivity to hydrogen peroxide J:216539
increased heart weight J:216539
oxidative stress J:216539
postnatal lethality, complete penetrance J:216539
Tg(CMV-Abcc9)1Ajo/?
either: (involves: BALB/c * CBA) or (involves: BALB/c * C57BL/6J * CBA) 		abnormal myocardial fiber physiology J:111456
abnormal response to cardiac infarction J:111456
abnormal sarcolemma morphology J:111456
decreased myocardial infarct size J:111456
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory