Nkx6-2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nkx6-2
NK6 homeobox 2
MGI:1352738

7 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nkx6-2^{tm1(cre/ERT2)Fsh}/Nkx6-2^{tm1(cre/ERT2)Fsh} involves: 129S6/SvEvTac * C57BL/6 * Swiss Webster	normal mortality/aging	J:155164
Nkx6-2^tm1Ercs/Nkx6-2^tm1Ercs involves: 129P2/OlaHsd * C57BL/6	no abnormal phenotype detected	J:71607
Nkx6-2^tm1Gow/Nkx6-2^tm1Gow involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac	abnormal myelination	J:94807
	abnormal nerve conduction	J:94807
	abnormal optic nerve morphology	J:94807
	axon degeneration	J:94807
	impaired coordination	J:94807
Nkx6-2^tm1Qiu/Nkx6-2^tm1Qiu Not Specified	no abnormal phenotype detected	J:69975

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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