Fscn1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fscn1
fascin actin-bundling protein 1
MGI:1352745

26 phenotypes from 2 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Fscn1^{Gt(OST124903)Lex}/Fscn1⁺ Tg(Dct-lacZ)A12Jkn/0 involves: C57BL/6 * CBA	abnormal melanoblast morphology	J:197025
Fscn1^{Gt(OST124903)Lex}/Fscn1^{Gt(OST124903)Lex} B6.129S5-Fscn1^{Gt(OST124903)Lex}	abnormal anterior commissure pars posterior morphology	J:205179
	abnormal axon morphology	J:205179
	abnormal breathing pattern	J:205179
	abnormal cell cycle	J:197025
	abnormal dendritic cell chemotaxis	J:169408
	abnormal dendritic cell physiology	J:169408
	abnormal fibroblast physiology	J:205179
	abnormal Langerhans cell physiology	J:169408
	abnormal melanoblast morphology	J:197025
	abnormal neurite morphology	J:205179
	absent gastric milk in neonates	J:205179
	belly spot	J:197025
	decreased body size	J:205179
	decreased digit pigmentation	J:197025
	decreased melanocyte number	J:197025
	decreased tail pigmentation	J:197025
	enlarged lateral ventricles	J:205179
	neonatal lethality, incomplete penetrance	J:205179
	nervous	J:205179
Fscn1^{Gt(OST124903)Lex}/Fscn1^{Gt(OST124903)Lex} involves: 129S5/SvEvBrd * C57BL/6	normal mortality/aging	J:205179
Fscn1^{Gt(OST124903)Lex}/Fscn1^{Gt(OST124903)Lex} Tg(Dct-lacZ)A12Jkn/0 involves: C57BL/6 * CBA	abnormal melanoblast migration	J:197025
	abnormal melanoblast morphology	J:197025
	belly spot	J:197025
Fscn1^{tm1.1(KOMP)Vlcg}/Fscn1⁺ C57BL/6N-Fscn1^{tm1.1(KOMP)Vlcg}/Ucd	abnormal behavior	J:211773
	decreased thigmotaxis	J:211773
	hyperactivity	J:211773
Fscn1^{tm1.1(KOMP)Vlcg}/Fscn1^{tm1.1(KOMP)Vlcg} C57BL/6N-Fscn1^{tm1.1(KOMP)Vlcg}/Ucd	preweaning lethality, complete penetrance	J:211773
	preweaning lethality, incomplete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24