Spdef Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Spdef
SAM pointed domain containing ets transcription factor
MGI:1353422

13 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Spdef^tm1.1Cle/Spdef^tm1.1Cle involves: 129P2/OlaHsd	abnormal laryngeal mucosa goblet cell morphology	J:154639
Spdef^tm1.1Cle/Spdef^tm1.1Cle involves: 129P2/OlaHsd	absent respiratory mucosa goblet cells	J:154639
Spdef^tm1.2Cle/Spdef^tm1.2Cle involves: 129P2/OlaHsd * FVB/N	abnormal crypts of Lieberkuhn morphology	J:154852
	abnormal intestinal goblet cell morphology	J:154852
	abnormal Paneth cell morphology	J:154852
	decreased Paneth cell number	J:154852
Spdef^tm1Shiv/Spdef^tm1Shiv involves: 129S4/SvJae	abnormal digestive system physiology	J:166876
	abnormal stomach glandular epithelium morphology	J:166876
	abnormal stomach mucosa morphology	J:166876
	abnormal stomach pyloric antrum morphology	J:166876
	prenatal lethality, incomplete penetrance	J:166876
	small intestinal inflammation	J:166876
	stomach inflammation	J:166876

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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