Opn4 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Opn4
opsin 4 (melanopsin)
MGI:1353425

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cnga3^tm1Biel/Cnga3^tm1Biel Gnat1^tm1Clma/Gnat1^tm1Clma Opn4^tm1Yau/Opn4^tm1Yau involves: 129 * C57BL/6	abnormal circardian behavior entrainment	J:84281
	impaired pupillary reflex	J:84281
	shortened circadian behavior period	J:84281
	normal vision/eye phenotype	J:84281
Dscam^tm1Pfu/Dscam^tm1Pfu Opn4^tm1(cre)Sapa/Opn4⁺ involves: 129 * C57BL/6	abnormal axon fasciculation	J:179393
	abnormal retina ganglion cell morphology	J:179393
Gt(ROSA)26Sor^{tm1(HBEGF)Awai}/Gt(ROSA)26Sor⁺ Opn4^tm1(cre)Sapa/Opn4⁺ involves: 129S * C57BL/6	abnormal circardian behavior entrainment	J:137151
	abnormal suprachiasmatic nucleus morphology	J:137151
	normal behavior/neurological phenotype	J:137151
	decreased retina ganglion cell number	J:137151
	impaired pupillary reflex	J:137151
Opn1mw^{tm1(OPN1LW)Nat}/Opn1mw^{tm1(OPN1LW)Nat} Opn4^tm1Yau/Opn4^tm1Yau involves: 129	abnormal visual contrast sensitivity	J:199509
Opn4^{tm1.1(cre)Saha}/Opn4⁺ Pou4f2^tm4(DTA)Whk/Pou4f2⁺ involves: 129S/SvEv * C57BL/6	abnormal circadian behavior period	J:174940
	normal behavior/neurological phenotype	J:174940
	decreased retina ganglion cell number	J:174940
	impaired pupillary reflex	J:174940
	normal vision/eye phenotype	J:174940
Opn4^{tm1.1(cre)Saha}/Opn4⁺ Pou4f2^tm4(DTA)Whk/Pou4f2⁺ Tg(CAG-Bgeo/ALPP)1Lbe/0 involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal innervation	J:174940
	abnormal olivary pretectal nucleus morphology	J:174940
	decreased retina ganglion cell number	J:174940
Opn4^{tm1.1(cre)Saha}/Opn4⁺ Pou4f2^tm2.1Nat/Pou4f2⁺ involves: 129 * C57BL/6	abnormal innervation	J:174940
	abnormal suprachiasmatic nucleus morphology	J:174940
Opn4^{tm1.1(cre)Saha}/Opn4^tm1Yau Pou4f2^tm4(DTA)Whk/Pou4f2⁺ involves: 129S/SvEv * C57BL/6	abnormal innervation	J:174940
	abnormal olivary pretectal nucleus morphology	J:174940
	decreased retina ganglion cell number	J:174940
Opn4^tm1Skay/Opn4^tm1Skay Pde6b^rd1/Pde6b^rd1 B6.Cg-Pde6b^rd1 Opn4^tm1Skay	abnormal eye physiology	J:227078
Opn4^tm1Skay/Opn4^tm1Skay Pde6b^rd1/Pde6b^rd1 involves: 129S1/SvImJ * C57BL/6	abnormal circardian behavior entrainment	J:137151
	impaired pupillary reflex	J:137151
Opn4^tm1Yau/Opn4^tm4(DTA)Saha involves: 129 * C57BL/6	abnormal retina ganglion cell morphology	J:134780
Opn4^tm1Yau/Opn4^tm4(DTA)Saha involves: 129 * C57BL/6	abnormal suprachiasmatic nucleus morphology	J:134780
Opn4^{tm2.1(cre/ERT2)Saha}/Opn4⁺ Pou4f2^tm2.1Nat/Pou4f2⁺ involves: 129 * C57BL/6	abnormal innervation	J:174940
	abnormal suprachiasmatic nucleus morphology	J:174940
Opn4^tm4(DTA)Saha/Opn4⁺ involves: 129 * C57BL/6	abnormal retina ganglion cell morphology	J:134780
Opn4^tm4(DTA)Saha/Opn4⁺ involves: 129 * C57BL/6	impaired pupillary reflex	J:134780
Opn4^tm4(DTA)Saha/Opn4^tm4(DTA)Saha involves: 129 * C57BL/6	abnormal circadian behavior phase	J:134780
	abnormal circardian behavior entrainment	J:134780
	abnormal locomotor circadian rhythm	J:134780
	abnormal retina ganglion cell morphology	J:134780
	abnormal suprachiasmatic nucleus morphology	J:134780
	abnormal visual pursuit	J:134780
	impaired pupillary reflex	J:134780
	prolonged circadian behavior period	J:134780

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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