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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
MGI:1353495
16 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Slc25a4tm1a(EUCOMM)Wtsi/Slc25a4tm1a(EUCOMM)Wtsi
C57BL/6N-Atm1Brd Slc25a4tm1a(EUCOMM)Wtsi/WtsiH 		decreased circulating chloride level J:211773
fusion of vertebral arches J:211773
improved glucose tolerance J:211773
increased blood urea nitrogen level J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating calcium level J:211773
increased circulating insulin level J:211773
increased heart weight J:211773
Slc25a4tm1Dwa/Slc25a4+
involves: 129 * C57BL/6J 		no abnormal phenotype detected J:41256
Slc25a4tm2Dwa/Slc25a4tm2Dwa
involves: 129S4/SvJae * C57BL/6J 		abnormal aerobic respiration J:41256
abnormal blood homeostasis J:41256
abnormal exercise endurance J:41256
cardiac hypertrophy J:41256
increased circulating alanine level J:41256
increased circulating lactate level J:41256
myopathy J:41256
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory