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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mapk8ip3
mitogen-activated protein kinase 8 interacting protein 3
MGI:1353598
43 phenotypes from 4 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Mapk8ip3tm1.1Ysok/Mapk8ip3tm1.1Ysok
involves: 129P2/OlaHsd * C57BL/6J 		abnormal dorsal telencephalic commissure morphology J:141459
neonatal lethality, complete penetrance J:141459
Mapk8ip3tm1Plhn/Mapk8ip3tm1Plhn
involves: 129S4/SvJae * C57BL/6 		abnormal lung development J:136735
abnormal lung saccule morphology J:136735
abnormal lung vasculature morphology J:136735
cyanosis J:136735
neonatal lethality, complete penetrance J:136735
respiratory failure J:136735
Mapk8ip3tm1Plhn/Mapk8ip3tm1Plhn
involves: 129S4/SvJae * C57BL/6J 		abnormal anterior commissure morphology J:95744
abnormal anterior commissure pars anterior morphology J:95744
abnormal anterior commissure pars posterior morphology J:95744
abnormal axon guidance J:95744
abnormal cerebral cortex morphology J:95744
abnormal cerebral cortex pyramidal cell morphology J:95744
abnormal CNS glial cell morphology J:95744
abnormal corpus callosum morphology J:95744
abnormal cortical marginal zone morphology J:95744
abnormal diencephalon morphology J:95744
abnormal frontal lobe morphology J:95744
abnormal hippocampal fimbria morphology J:95744
abnormal hippocampus morphology J:95744
abnormal neuronal migration J:95744
abnormal optic tract morphology J:95744
abnormal parietal lobe morphology J:95744
abnormal subplate morphology J:95744
abnormal telencephalon development J:95744
abnormal telencephalon morphology J:95744
abnormal thalamus morphology J:95744
cyanosis J:95744
enlarged brain ventricles J:95744
increased hippocampal fornix size J:95744
increased optic chiasm size J:95744
neonatal lethality, complete penetrance J:95744
respiratory failure J:95744
thin cortical plate J:95744
Mapk8ip3tm1Rjd/Mapk8ip3tm1Rjd
B6.129S6-Mapk8ip3tm1Rjd 		abnormal axon guidance J:85160
abnormal brain commissure morphology J:85160
abnormal CNS synaptic transmission J:85160
abnormal pulmonary alveolus morphology J:85160
abnormal telencephalon development J:85160
anoxia J:85160
atelectasis J:85160
decreased brain size J:85160
dilated lateral ventricle J:85160
perinatal lethality, complete penetrance J:85160
respiratory failure J:85160
thick pulmonary interalveolar septum J:85160
Mapk8ip3tm1Ysok/Mapk8ip3tm1Ysok
involves: 129P2/OlaHsd * C57BL/6J 		no abnormal phenotype detected J:141459
Mapk8ip3tm1Ysok/Mapk8ip3tm1Ysok
Tg(Nes-cre)1Kln/0
involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL 		abnormal dorsal telencephalic commissure morphology J:141459
neonatal lethality, incomplete penetrance J:141459
postnatal lethality, complete penetrance J:141459
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory