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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Zbtb18
zinc finger and BTB domain containing 18
MGI:1353609
30 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Zbtb18tm1.1Nda/Zbtb18tm1.1Nda
Tg(Nes-cre)1Kln/0
involves: C57BL/6 * SJL 		abnormal cerebellar cortex morphology J:184434
abnormal cerebral cortex morphology J:184434
abnormal nervous system development J:184434
abnormal neuron differentiation J:184434
abnormal neuronal migration J:184434
abnormal radial glial cell morphology J:184434
abnormal stratification in cerebral cortex J:184434
absent corpus callosum J:184434
decreased body size J:184434
decreased brain size J:184434
enlarged brain ventricles J:184434
increased neuron apoptosis J:184434
postnatal lethality J:184434
thin cerebral cortex J:184434
Zbtb18tm1Haok/Zbtb18tm1Haok
involves: 129 		abnormal axon extension J:196306
abnormal axon morphology J:196306
abnormal neuron differentiation J:196306
abnormal neuronal migration J:196306
abnormal neuronal precursor proliferation J:196306
abnormal subplate morphology J:196306
increased neuron apoptosis J:196306
increased neuronal precursor cell number J:196306
Zbtb18tm1Haok/Zbtb18tm1Haok
involves: 129/Sv * C57BL/6 		abnormal cerebellar foliation J:150768
abnormal cortical ventricular zone morphology J:150768
abnormal hippocampus granule cell layer J:150768
abnormal hippocampus morphology J:150768
abnormal hippocampus pyramidal cell layer J:150768
abnormal neocortex morphology J:150768
abnormal neuron physiology J:150768
abnormal postnatal subventricular zone morphology J:150768
decreased neuron number J:150768
increased neuron apoptosis J:150768
neonatal lethality, complete penetrance J:150768
small hippocampus J:150768
Zbtb18tm2.1Haok/Zbtb18tm2.1Haok
involves: 129 		abnormal neuron differentiation J:196306
abnormal neuronal migration J:196306
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory