Angptl3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Angptl3
angiopoietin-like 3
MGI:1353627

17 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Angptl3^hypl/Angptl3^hypl involves: KK/Snk	decreased circulating cholesterol level	J:75358
	decreased circulating free fatty acids level	J:75358
	decreased circulating HDL cholesterol level	J:75358
	decreased circulating LDL cholesterol level	J:75358
	decreased circulating triglyceride level	J:75358
	decreased circulating VLDL cholesterol level	J:75358
	decreased gonadal fat pad weight	J:75358
	decreased triglyceride level	J:75358
	increased lipoprotein lipase activity	J:75358
Angptl3^tm1Akos/Angptl3^tm1Akos involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal adipose tissue phenotype	J:103363
	decreased circulating cholesterol level	J:103363
	decreased circulating triglyceride level	J:103363
	increased lipoprotein lipase activity	J:103363
Angptl3^tm1Kfuj/Angptl3^tm1Kfuj B6.129S1-Angptl3^tm1Kfuj	abnormal liver physiology	J:107479
	decreased circulating cholesterol level	J:107479
	decreased circulating free fatty acids level	J:107479
	decreased circulating triglyceride level	J:107479
	decreased circulating VLDL cholesterol level	J:107479
	decreased epididymal fat pad weight	J:107479
	increased liver weight	J:107479
Angptl3^tm1Lex/Angptl3^tm1Lex involves: 129S5/SvEvBrd * C57BL/6	decreased circulating triglyceride level	J:149912
Angptl3^{tm2b(KOMP)Wtsi}/Angptl3^{tm2b(KOMP)Wtsi} C57BL/6N-Angptl3^{tm2b(KOMP)Wtsi}/Ccpcz	decreased circulating cholesterol level	J:211773
	decreased circulating HDL cholesterol level	J:211773
	decreased circulating triglyceride level	J:211773
	enlarged lymph nodes	J:211773
	enlarged uterus	J:211773
	hydrometra	J:211773
	increased fasting circulating glucose level	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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