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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		E2f6
E2F transcription factor 6
MGI:1354159
18 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Bmi1tm1Brn/Bmi1+
E2f6tm1Lees/E2f6+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		cervical vertebral transformation J:134271
lumbar vertebral transformation J:134271
thoracic vertebral transformation J:134271
Bmi1tm1Brn/Bmi1+
E2f6tm1Lees/E2f6tm1Lees
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		cervical vertebral transformation J:134271
lumbar vertebral transformation J:134271
thoracic vertebral transformation J:134271
Bmi1tm1Brn/Bmi1tm1Brn
E2f6tm1Lees/E2f6+
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal vertebrae morphology J:134271
cervical vertebral transformation J:134271
lumbar vertebral transformation J:134271
thoracic vertebral transformation J:134271
Bmi1tm1Brn/Bmi1tm1Brn
E2f6tm1Lees/E2f6tm1Lees
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 		abnormal bone marrow cell morphology/development J:134271
abnormal cell cycle J:134271
abnormal vertebrae morphology J:134271
anemia J:134271
ataxia J:134271
cerebellum hypoplasia J:134271
cervical vertebral transformation J:134271
decreased bone marrow cell number J:134271
decreased cell proliferation J:134271
decreased double-positive T cell number J:134271
decreased hematopoietic cell number J:134271
early cellular replicative senescence J:134271
lumbar vertebral transformation J:134271
postnatal growth retardation J:134271
postnatal lethality, incomplete penetrance J:134271
premature death J:134271
prenatal lethality, incomplete penetrance J:134271
thoracic vertebral transformation J:134271
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory