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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tmprss2
transmembrane protease, serine 2
MGI:1354381
13 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ergtm1.1Sho/Ergtm1.1Sho
Ptentm1Hwu/Ptentm1Hwu
Tmprss2tm3Sho/Tmprss2tm3Sho
Tg(Pbsn-cre)4Prb/0
involves: 129S4/SvJae * C57BL/6 * DBA/2 		increased prostate gland adenocarcinoma incidence J:212219
normal mortality/aging J:212219
Ptentm1.1Hwu/Pten+
Tmprss2tm1.1(ERG)Sho/Tmprss2tm1.1(ERG)Sho
involves: 129S4/SvJae * C57BL/6 * DBA/2 		increased prostate intraepithelial neoplasia incidence J:212219
Ptentm1.1Hwu/Pten+
Tmprss2tm2.1(ETV1)Sho/Tmprss2tm2.1(ETV1)Sho
involves: 129S4/SvJae * C57BL/6 * DBA/2 		increased prostate intraepithelial neoplasia incidence J:212219
Ptentm1Hwu/Pten+
Tmprss2tm2.1(ETV1)Sho/Tmprss2tm2.1(ETV1)Sho
Tg(Pbsn-cre)4Prb/0
involves: 129S4/SvJae * C57BL/6 * DBA/2 		increased prostate gland adenocarcinoma incidence J:212219
premature death J:212219
prostate gland cyst J:212219
Tg(DPP4)2Nnag/0
Tmprss2tm1(KOMP)Vlcg/Tmprss2tm1(KOMP)Vlcg
involves: C57BL/6NCr * C57BL/6NTac * DBA 		abnormal cytokine secretion J:283077
decreased susceptibility to Coronaviridae infection J:283077
Tg(TRAMP)8247Ng/0
Tmprss2tm1Psn/Tmprss2tm1Psn
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		decreased metastatic potential J:217920
increased tumor growth/size J:217920
Tmprss2tm1.1(ERG)Sho/Tmprss2tm1.1(ERG)Sho
involves: C57BL/6 * DBA/2 		normal neoplasm J:212219
normal reproductive system phenotype J:212219
Tmprss2tm2.1(ETV1)Sho/Tmprss2tm2.1(ETV1)Sho
involves: C57BL/6 * DBA/2 		abnormal testosterone level J:212219
normal neoplasm J:212219
prostate gland inflammation J:212219
normal reproductive system phenotype J:212219
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory