Socs1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Socs1
suppressor of cytokine signaling 1
MGI:1354910

19 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ifng^tm1Ts/Ifng⁺ Socs1^tm1Wehi/Socs1^tm1Wehi involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6	decreased survivor rate	J:57474
	premature death	J:57474
Ifng^tm1Ts/Ifng^tm1Ts Socs1^tm1Jni/Socs1^tm1Jni involves: 129S7/SvEvBrd	increased interleukin-17 secretion	J:132905
Ifng^tm1Ts/Ifng^tm1Ts Socs1^tm1Wehi/Socs1^tm1Wehi involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6	abnormal lactation	J:70408
	abnormal lung vasculature morphology	J:57474
	abnormal mammary gland growth during pregnancy	J:70408
	enlarged thymus medulla	J:57474
	normal hematopoietic system phenotype	J:57474
	mammary gland alveolar hyperplasia	J:70408
	normal mortality/aging	J:57474, J:70408
Prlr^tm1Cnp/Prlr⁺ Socs1^tm1Wehi/Socs1⁺ involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas * C57BL/6	normal endocrine/exocrine gland phenotype	J:70408
	normal reproductive system phenotype	J:70408
Socs1^tm1Kish/Socs1^tm1Kish Stat1^tm1Rds/Stat1^tm1Rds involves: 129/Sv * 129P2/OlaHsd * C57BL/6	decreased body size	J:69472
	enlarged liver	J:69472
	normal immune system phenotype	J:69472
	increased activated T cell number	J:69472
	liver inflammation	J:69472
	postnatal growth retardation	J:69472
	premature death	J:69472
	thymus atrophy	J:69472
Socs1^tm1Kish/Socs1^tm1Kish Stat6^tm1Aki/Stat6^tm1Aki involves: 129P2/OlaHsd * C57BL/6	decreased body size	J:69472
	enlarged liver	J:69472
	normal immune system phenotype	J:69472
	increased activated T cell number	J:69472
	liver inflammation	J:69472
	postnatal growth retardation	J:69472
	premature death	J:69472
	thymus atrophy	J:69472

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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