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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dlc1
deleted in liver cancer 1
MGI:1354949
25 phenotypes from 3 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dlc1Gt(XE082)Byg/Dlc1Gt(XE082)Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal blood cell morphology/development J:189950
abnormal heart atrium morphology J:189950
abnormal neural tube morphology J:189950
abnormal placenta labyrinth morphology J:189950
abnormal placental labyrinth vasculature morphology J:189950
abnormal vitelline vasculature morphology J:189950
delayed brain development J:189950
embryo tissue necrosis J:189950
embryonic growth retardation J:189950
enhanced wound healing J:189950
enlarged heart J:189950
increased fibroblast cell migration J:189950
open neural tube J:189950
pale yolk sac J:189950
prenatal lethality, complete penetrance J:189950
thin ventricular wall J:189950
Dlc1tm1.1Lowy/Dlc1tm1.1Lowy
involves: 129 * C57BL/6 		no abnormal phenotype detected J:192878
Dlc1tm1.1Lowy/Dlc1tm1.1Lowy
involves: 129 * C57BL/6 		abnormal cell physiology J:192878
Dlc1tm1Lec/Dlc1+
involves: 129P2/OlaHsd * C57BL/6 		no abnormal phenotype detected J:96194
Dlc1tm1Lec/Dlc1tm1Lec
involves: 129P2/OlaHsd * C57BL/6 		abnormal brain development J:96194
abnormal cell adhesion J:96194
abnormal forebrain development J:96194
abnormal heart development J:96194
abnormal hindbrain development J:96194
abnormal pharyngeal arch morphology J:96194
abnormal placental labyrinth vasculature morphology J:96194
embryonic lethality during organogenesis, complete penetrance J:96194
open neural tube J:96194
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory