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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Uchl3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
MGI:1355274
15 phenotypes from 1 allele in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Uchl3tm1Tilg/Uchl3tm1Tilg
involves: 129S1/Sv * C57BL/6 		abnormal dorsal root ganglion morphology J:71819
abnormal retina layer morphology J:83810
abnormal retina outer nuclear layer morphology J:83810
abnormal skeletal muscle fiber morphology J:83810
axonal dystrophy J:71819
decreased body weight J:71819
normal immune system phenotype J:61093
normal reproductive system phenotype J:61093
Uchl3tm1Tilg/Uchl3tm1Tilg
involves: 129S1/Sv * C57BL/6J 		abnormal photoreceptor inner segment morphology J:110169
abnormal photoreceptor outer segment morphology J:110169
abnormal retina outer nuclear layer morphology J:110169
abnormal retina vasculature morphology J:110169
increased retina apoptosis J:110169
increased susceptibility to age-related retinal degeneration J:110169
thin retina outer nuclear layer J:110169
thin retina outer plexiform layer J:110169
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory