Il27ra Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il27ra
interleukin 27 receptor, alpha
MGI:1355318

24 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Il27ra^tm1Fjs/Il27ra^tm1Fjs B6.Cg-Il27ra^tm1Fjs	abnormal T-helper 1 physiology	J:94856
	decreased susceptibility to bacterial infection	J:94856
	increased lymphocyte cell number	J:94856
Il27ra^tm1Mak/Il27ra^tm1Mak B6.129P2-Il27ra^tm1Mak	abnormal T-helper 1 physiology	J:89509, J:116610
	decreased circulating interferon-gamma level	J:116610
	decreased interferon-gamma secretion	J:89509, J:116610
	decreased susceptibility to experimental autoimmune uveoretinitis	J:116610
	normal hematopoietic system phenotype	J:89509
	hepatic necrosis	J:88618
	normal immune system phenotype	J:88618
	increased circulating alanine transaminase level	J:88618
	increased circulating interferon-gamma level	J:88618
	increased circulating interleukin-1 beta level	J:88618
	increased circulating interleukin-4 level	J:88618
	increased circulating interleukin-6 level	J:88618
	increased circulating interleukin-12 level	J:88618
	increased circulating tumor necrosis factor level	J:88618
	increased interferon-gamma secretion	J:88618
	increased interleukin-4 secretion	J:88618
	increased susceptibility to bacterial infection	J:89509
	increased susceptibility to injury	J:88618
	increased susceptibility to parasitic infection	J:89509
	increased susceptibility to xenobiotic induced morbidity/mortality	J:88618
	increased T cell proliferation	J:89509
Il27ra^tm1Mak/Il27ra^tm1Mak involves: 129P2/OlaHsd * C57BL/6	increased susceptibility to induced arthritis	J:151552

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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