Il27ra Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Il27ra
interleukin 27 receptor, alpha
MGI:1355318

18 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Fas^lpr/Fas^lpr Il27ra^tm1Mak/Il27ra^tm1Mak MRL.Cg-Il27ra^tm1Mak Fas^lpr	abnormal T-helper 2 physiology	J:122148
	decreased anti-double stranded DNA antibody level	J:122148
	decreased blood urea nitrogen level	J:122148
	decreased circulating creatinine level	J:122148
	decreased IgG2a level	J:122148
	decreased interferon-gamma secretion	J:122148
	decreased susceptibility to systemic lupus erythematosus	J:122148
	extended life span	J:122148
	glomerulonephritis	J:122148
	normal immune system phenotype	J:122148
	increased circulating interleukin-4 level	J:122148
	increased circulating interleukin-5 level	J:122148
	increased IgE level	J:122148
	increased IgG1 level	J:122148
Il10^tm1Cgn/Il10^tm1Cgn Il27ra^tm1Mak/Il27ra^tm1Mak involves: 129P2/OlaHsd * C57BL/6	abnormal T-helper 1 physiology	J:136179
	abnormal T-helper 2 physiology	J:136179
	colitis	J:136179
	decreased interferon-gamma secretion	J:136179
	decreased susceptibility to induced colitis	J:136179
	extended life span	J:136179
	increased interleukin-13 secretion	J:136179

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24