Olig2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Olig2
oligodendrocyte transcription factor 2
MGI:1355331

26 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Emx1^tm1(cre)Ito/Emx1⁺ Olig2^tm1Qrlu/Olig2^tm1Qrlu involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6	abnormal myelination	J:105071
Olig2^{tm1(cre/Esr1)Htak}/Olig2^{tm1(cre/Esr1)Htak} involves: BALB/c * C57BL/6 * C57BL/6NCrj * CBA	abnormal neuronal migration	J:77821
	abnormal posture	J:77821
	abnormal reflex	J:77821
	abnormal spinal cord morphology	J:77821
	abnormal spinal cord ventral horn morphology	J:77821
	aphagia	J:77821
	decreased motor neuron number	J:77821
	decreased oligodendrocyte progenitor number	J:77821
	hypotonia	J:77821
	neonatal lethality, complete penetrance	J:77821
Olig2^{tm1(cre/Esr1)Htak}/Olig2^{tm1(cre/Esr1)Htak} involves: C57BL/6NCrlj * CBA/JNCrlj	abnormal cell differentiation	J:203419
	abnormal dorsal root ganglion morphology	J:182750
	abnormal proprioceptive neuron morphology	J:182750
	abnormal sensory neuron innervation pattern	J:182750
	abnormal sensory neuron morphology	J:182750
	decreased motor neuron number	J:182750
	normal nervous system phenotype	J:182750
Olig2^tm1Qrlu/Olig2^tm1Qrlu Foxg1^tm1(cre)Skm/Foxg1⁺ involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6	abnormal myelination	J:105071
Olig2^tm1Qrlu/Olig2^tm1Qrlu Tg(GFAP-cre)25Mes/? involves: 129S4/SvJae * C57BL/6J * FVB/N	abnormal corpus callosum morphology	J:105071
	abnormal oligodendrocyte morphology	J:105071
	limb grasping	J:105071
	tremors	J:105071
Olig2^tm1Rth/Olig2^tm1Rth involves: 129S4/SvJae * C57BL/6J	abnormal breathing pattern	J:75868
	abnormal hindbrain development	J:75868
	abnormal ventral interneuron 2 morphology	J:75868
	decreased motor neuron number	J:75868
	decreased oligodendrocyte progenitor number	J:75868
	no spontaneous movement	J:75868
	preweaning lethality, complete penetrance	J:75868

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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