About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Plrg1
pleiotropic regulator 1
MGI:1858197
14 phenotypes from 2 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Plrg1tm1Jcbr/Plrg1tm1Jcbr
Not Specified
embryonic lethality before implantation, complete penetrance J:149153
Plrg1tm2Jcbr/Plrg1tm2Jcbr
Not Specified
abnormal cell cycle J:149153
decreased cell proliferation J:149153
Plrg1tm2Jcbr/Plrg1tm2Jcbr
Tg(Ckmm-cre)5Khn/0
involves: FVB
abnormal heart ventricle morphology J:149153
decreased heart ventricle muscle contractility J:149153
dilated cardiomyopathy J:149153
dilated heart J:149153
dilated heart left ventricle J:149153
dilated heart right ventricle J:149153
increased cardiomyocyte apoptosis J:149153
premature death J:149153
thin ventricular wall J:149153
Plrg1tm2Jcbr/Plrg1tm2Jcbr
Tg(Syn1-cre)671Jxm/0
involves: C57BL/6 * CBA
increased neuron apoptosis J:149153
postnatal lethality, complete penetrance J:149153

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory