Ppp1r3c Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppp1r3c
protein phosphatase 1, regulatory subunit 3C
MGI:1858229

22 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppp1r3c^tm1Adpr/Ppp1r3c^tm1Adpr B6.Cg-Ppp1r3c^tm1Adpr	abnormal glucose homeostasis	J:242758
	normal homeostasis/metabolism phenotype	J:242758
	increased energy expenditure	J:242758
	increased insulin sensitivity	J:242758
	increased muscle cell glucose uptake	J:242758
	normal mortality/aging	J:242758
Ppp1r3c^tm1Adpr/Ppp1r3c^tm1Adpr involves: C57BL/6J	abnormal glycogen homeostasis	J:242755
Ppp1r3c^tm1Ars/Ppp1r3c⁺ B6.129-Ppp1r3c^tm1Ars	abnormal enzyme/coenzyme activity	J:83297
	abnormal glucose homeostasis	J:83297
	abnormal glycogen homeostasis	J:83297
	decreased adipose tissue glycogen level	J:83297
	decreased cardiac muscle glycogen level	J:83297
	decreased glycogen level	J:83297
	decreased liver glycogen level	J:83297
	decreased skeletal muscle cell glucose uptake	J:83297
	decreased skeletal muscle glycogen level	J:83297
	impaired glucose tolerance	J:83297
	increased circulating insulin level	J:83297
	increased circulating leptin level	J:83297
	increased circulating triglyceride level	J:83297
	increased heart weight	J:83297
	increased skeletal muscle triglyceride level	J:83297
	insulin resistance	J:83297
Ppp1r3c^tm1Ars/Ppp1r3c^tm1Ars B6.129-Ppp1r3c^tm1Ars	prenatal lethality, complete penetrance	J:83297

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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