Tnk2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tnk2
tyrosine kinase, non-receptor, 2
MGI:1858308

10 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tnk2^em1(IMPC)Tcp/Tnk2^em1(IMPC)Tcp C57BL/6N-Tnk2^em1(IMPC)Tcp/Tcp	enlarged lymph nodes	J:211773
Tnk2^tm1.2Npma/Tnk2^tm1.2Npma B6(Cg)-Tnk2^tm1.2Npma	abnormal regulatory T cell number	J:341740
	abnormal T cell physiology	J:341740
	decreased tumor growth/size	J:341740
	increased activated T cell number	J:341740
	increased circulating interferon-gamma level	J:341740
	increased circulating interleukin-2 level	J:341740
	increased effector memory CD8-positive, alpha-beta T cell number	J:341740
	increased interferon level	J:341740
	increased interleukin level	J:341740

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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