Keap1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Keap1
kelch-like ECH-associated protein 1
MGI:1858732

16 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Keap1^tm1.1Sbis/Keap1^tm1.1Sbis Tg(Scgb1a1-cre)1Grau/0 involves: C57BL/6J	abnormal club cell morphology	J:170960
	abnormal lung epithelium morphology	J:170960
	decreased susceptibility to injury	J:170960
Keap1^tm1Mym/Keap1^tm1Mym involves: 129P2/OlaHsd * C57BL/6J	abnormal esophageal epithelium morphology	J:86392
	abnormal stomach glandular epithelium morphology	J:86392
	abnormal stomach non-glandular epithelium morphology	J:86392
	decreased body size	J:86392
	decreased body weight	J:86392
	hyperkeratosis	J:86392
	increased stomach mucosa thickness	J:86392
	postnatal growth retardation	J:86392
	postnatal lethality, complete penetrance	J:86392
	scaly skin	J:86392
	small stomach	J:86392
Keap1^tm1Mym/Keap1^tm2Mym Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: 129P2/OlaHsd * C57BL/6 * DBA	decreased physiological sensitivity to xenobiotic	J:103791
	decreased susceptibility to xenobiotic induced morbidity/mortality	J:103791

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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