Arhgef5 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Arhgef5
Rho guanine nucleotide exchange factor 5
MGI:1858952

6 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Arhgef5^tm1.1Dwu/Arhgef5^tm1.1Dwu involves: 129S1/Sv * 129S6/SvEvTac	abnormal CD4-positive, alpha-beta T cell physiology	J:157812
	abnormal dendritic cell physiology	J:157812
	decreased eosinophil cell number	J:157812
	decreased interleukin-4 secretion	J:157812
	normal immune system phenotype	J:157812
Arhgef5^tm1.2Meg/Arhgef5^tm1.2Meg involves: 129S4/SvJae	increased CNS synapse formation	J:167914

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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