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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Batf
basic leucine zipper transcription factor, ATF-like
MGI:1859147
17 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Batftm1.1Ejt/Batftm1.1Ejt
involves: 129S/Sv * C57BL/6 * FVB/N 		abnormal class switch recombination J:160935
abnormal T-helper 2 cell differentiation J:160935
absent germinal center B cells J:160935
decreased CD4-positive, alpha-beta T cell number J:160935
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number J:160935
decreased IgA level J:160935
decreased IgE level J:160935
decreased IgG1 level J:160935
decreased IgG2c level J:160935
decreased IgM level J:160935
decreased interleukin-4 secretion J:160935
decreased interleukin-17 secretion J:160935
decreased T follicular helper cell number J:160935
decreased T-helper 17 cell number J:160935
Batftm1.1Kmm/Batftm1.1Kmm
129S6/SvEvTac-Batftm1.1Kmm 		abnormal CD4-positive T cell differentiation J:150643
decreased interleukin-17 secretion J:150643
decreased interleukin-21 secretion J:150643
decreased susceptibility to experimental autoimmune encephalomyelitis J:150643
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory