Rnf10 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rnf10
ring finger protein 10
MGI:1859162

64 phenotypes from 5 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rnf10^em1(IMPC)Bay/Rnf10^em1(IMPC)Bay C57BL/6N-Rnf10^em1(IMPC)Bay/Bay	abnormal retina blood vessel morphology	J:211773
	decreased prepulse inhibition	J:211773
	decreased total retina thickness	J:211773
	increased vertical activity	J:211773
Rnf10^em1(IMPC)J/Rnf10^em1(IMPC)J C57BL/6NJ-Rnf10^em1(IMPC)J/J	abnormal bone structure	J:211773
	decreased exploration in new environment	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular volume	J:211773
	increased bone mineral content	J:211773
	increased vertical activity	J:211773
	limb grasping	J:211773
Rnf10^em1(IMPC)Mbp/Rnf10^em1(IMPC)Mbp C57BL/6N-Rnf10^em1(IMPC)Mbp/Ucd	abnormal eye morphology	J:211773
	abnormal kidney morphology	J:211773
	anophthalmia	J:211773
	decreased brain weight	J:211773
	increased circulating alanine transaminase level	J:211773
	increased circulating aspartate transaminase level	J:211773
	increased circulating glucose level	J:211773
Rnf10^{tm1a(KOMP)Wtsi}/Rnf10^{tm1a(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1a(KOMP)Wtsi}/Wtsi	decreased body weight	J:175295
	decreased circulating cholesterol level	J:175295
	decreased circulating HDL cholesterol level	J:175295
	increased body weight	J:175295
	increased circulating cholesterol level	J:175295
	increased circulating HDL cholesterol level	J:175295
	increased circulating triglyceride level	J:175295
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10⁺ C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Ieg	increased grip strength	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10⁺ C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/MbpMmucd	increased circulating HDL cholesterol level	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10⁺ C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Ucd	decreased circulating serum albumin level	J:211773
	decreased circulating triglyceride level	J:211773
	decreased total body fat amount	J:211773
	enlarged heart	J:211773
	increased heart weight	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Bay	abnormal behavior	J:211773
	abnormal spleen morphology	J:211773
	decreased prepulse inhibition	J:211773
	hyperactivity	J:211773
	increased vertical activity	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/H	abnormal gait	J:211773
	decreased anxiety-related response	J:211773
	decreased circulating alkaline phosphatase level	J:211773
	decreased circulating total protein level	J:211773
	decreased hemoglobin content	J:211773
	decreased prepulse inhibition	J:211773
	hyperactivity	J:211773
	increased large unstained cell number	J:211773
	increased red blood cell distribution width	J:211773
	limb grasping	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Ics	abnormal behavior	J:211773
	abnormal freezing behavior	J:211773
	decreased body length	J:211773
	decreased circulating cholesterol level	J:211773
	decreased circulating HDL cholesterol level	J:211773
	decreased circulating serum albumin level	J:211773
	decreased exploration in new environment	J:211773
	decreased grip strength	J:211773
	decreased locomotor activity	J:211773
	decreased lymphocyte cell number	J:211773
	decreased prepulse inhibition	J:211773
	decreased total retina thickness	J:211773
	improved glucose tolerance	J:211773
	increased anxiety-related response	J:211773
	increased monocyte cell number	J:211773
	increased vertical activity	J:211773
	shortened QT interval	J:211773
	shortened ST segment	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Ieg	decreased circulating serum albumin level	J:211773
	decreased circulating total protein level	J:211773
	decreased locomotor activity	J:211773
	decreased vertical activity	J:211773
	hyperactivity	J:211773
	increased circulating triglyceride level	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/J	abnormal auditory brainstem response	J:211773
	convulsive seizures	J:211773
	decreased circulating glucose level	J:211773
	decreased fasting circulating glucose level	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular hemoglobin concentration	J:211773
	decreased prepulse inhibition	J:211773
	decreased thigmotaxis	J:211773
	hyperactivity	J:211773
	increased circulating sodium level	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/MbpMmucd	preweaning lethality, incomplete penetrance	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Rbrc	decreased bone mineral density	J:211773
	decreased hemoglobin content	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	decreased mean corpuscular volume	J:211773
	increased bone mineral content	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Ucd	preweaning lethality, incomplete penetrance	J:211773
Rnf10^{tm1b(KOMP)Wtsi}/Rnf10^{tm1b(KOMP)Wtsi} C57BL/6N-Rnf10^{tm1b(KOMP)Wtsi}/Wtsi	abnormal auditory brainstem response	J:211773
	abnormal tibia morphology	J:211773
	absent pinna reflex	J:211773
	decreased body length	J:211773
	decreased grip strength	J:211773
	increased bone mineral content	J:211773
	increased circulating creatinine level	J:211773
	increased lean body mass	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24