Pmm2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pmm2
phosphomannomutase 2
MGI:1859214

43 phenotypes from 6 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pmm2^tm1.1Cknr/Pmm2^tm1.1Cknr involves: C57BL/6J	no abnormal phenotype detected	J:180794
Pmm2^tm1.1Cknr/Pmm2^tm2.1Cknr involves: C57BL/6J	abnormal cell physiology	J:180794
	abnormal embryonic neuroepithelium morphology	J:180794
	abnormal embryonic tissue morphology	J:180794
	abnormal extraembryonic tissue morphology	J:180794
	abnormal head mesenchyme morphology	J:180794
	abnormal myocardium layer morphology	J:180794
	abnormal trophoblast giant cell morphology	J:180794
	decreased body length	J:180794
	normal embryo phenotype	J:180794
	embryonic growth retardation	J:180794
	embryonic lethality during organogenesis, complete penetrance	J:180794
	hemorrhage	J:180794
Pmm2^tm1.1Jins/Pmm2^tm1.1Jins involves: 129S6/SvEvTac * C57BL/6J	prenatal lethality, incomplete penetrance	J:236704
Pmm2^tm1.1Jins/Pmm2^tm2.1Jins involves: 129S6/SvEvTac * C57BL/6J	abnormal blood homeostasis	J:236704
	abnormal eye morphology	J:236704
	abnormal myocardial fiber morphology	J:236704
	abnormal myocardium layer morphology	J:236704
	abnormal proximal convoluted tubule morphology	J:236704
	abnormal vertebral column morphology	J:236704
	decreased body size	J:236704
	decreased body weight	J:236704
	decreased circulating antithrombin level	J:236704
	decreased circulating insulin-like growth factor I level	J:236704
	dilated proximal convoluted tubule	J:236704
	normal hematopoietic system phenotype	J:236704
	hypotonia	J:236704
	kyphosis	J:236704
	large posterior fontanelle	J:236704
	Mallory bodies	J:236704
	normal nervous system phenotype	J:236704
	premature death	J:236704
	prenatal lethality, incomplete penetrance	J:236704
	proximal convoluted tubule brush border loss	J:236704
	normal respiratory system phenotype	J:236704
	thin interventricular septum	J:236704
	thin ventricular wall	J:236704
Pmm2^{tm1b(EUCOMM)Hmgu}/Pmm2⁺ C57BL/6N-Pmm2^{tm1b(EUCOMM)Hmgu}/Tcp	enlarged lymph nodes	J:211773
	increased blood urea nitrogen level	J:211773
Pmm2^{tm1b(EUCOMM)Hmgu}/Pmm2^{tm1b(EUCOMM)Hmgu} C57BL/6N-Pmm2^{tm1b(EUCOMM)Hmgu}/Tcp	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Pmm2^tm1Cthl/Pmm2^tm1Cthl involves: 129P2/OlaHsd * C57BL/6	embryonic lethality, complete penetrance	J:111420
Pmm2^tm1Cthl/Pmm2^tm1Cthl involves: 129P2/OlaHsd * C57BL/6	maternal effect	J:111420
Pmm2^tm2.1Cknr/Pmm2^tm2.1Cknr involves: C57BL/6J	embryonic lethality, complete penetrance	J:180794
Pmm2^tm2.1Jins/Pmm2^tm2.1Jins involves: 129S6/SvEvTac * C57BL/6J	prenatal lethality, complete penetrance	J:236704

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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