Dnmt3l Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dnmt3l
DNA methyltransferase 3-like
MGI:1859287

29 phenotypes from 7 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dnmt3l^em1(IMPC)Bay/Dnmt3l^em1(IMPC)Bay C57BL/6N-Dnmt3l^em1(IMPC)Bay/BayMmucd	female infertility	J:211773
	male infertility	J:211773
Dnmt3l^em1Hsas/Dnmt3l^em1Hsas C57BL/6J-Dnmt3l^em1Hsas	abnormal DNA methylation during gametogenesis	J:347433
	abnormal imprinting	J:347433
	normal reproductive system phenotype	J:347433
Dnmt3l^{tm1b(EUCOMM)Hmgu}/Dnmt3l^{tm1b(EUCOMM)Hmgu} C57BL/6N-Dnmt3l^{tm1b(EUCOMM)Hmgu}/Ieg	increased bone mineral density	J:211773
	increased mean corpuscular hemoglobin	J:211773
	persistence of hyaloid vascular system	J:211773
	small testis	J:211773
Dnmt3l^tm1Bes/Dnmt3l^tm1Bes involves: 129S6/SvEvTac	abnormal chorion morphology	J:73452
	abnormal ectoplacental cone morphology	J:73452
	abnormal oogenesis	J:73452
	abnormal spermatogenesis	J:128710
	abnormal trophoblast layer morphology	J:73452
	abnormal visceral yolk sac endoderm morphology	J:73452
	azoospermia	J:73452
	decreased male germ cell number	J:128710
	exencephaly	J:73452
	failure of chorioallantoic fusion	J:73452
	female infertility	J:73452
	increased trophoblast giant cell number	J:73452
	infertility	J:73452
	male infertility	J:73452
	pericardial edema	J:73452
	prenatal lethality, complete penetrance	J:73452
	small testis	J:73452
Dnmt3l^tm1Enl/Dnmt3l^tm1Enl involves: 129S4/SvJae	abnormal chorion morphology	J:75938
	abnormal oogenesis	J:75938
	abnormal spermiogenesis	J:75938
	infertility	J:75938
	open neural tube	J:75938
	prenatal lethality, complete penetrance	J:75938
	small testis	J:75938
Dnmt3l^tm1Scot/Dnmt3l^tm1Scot C57BL/6-Dnmt3l^tm1Scot	abnormal seminiferous tubule epithelium morphology	J:97190
	arrest of male meiosis	J:97190
	azoospermia	J:97190
	infertility	J:97190
	small gonad	J:97190
Dnmt3l^tm2Bes/Dnmt3l^tm2Bes involves: 129	no abnormal phenotype detected	J:123743

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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