Nup210 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nup210
nucleoporin 210
MGI:1859555

21 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nup210^em1(IMPC)Mbp/Nup210^em1(IMPC)Mbp C57BL/6NCrl-Nup210^em1(IMPC)Mbp/MbpMmucd	abnormal liver morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	small liver	J:211773
Nup210^enuI476T/Nup210^enuI476T involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal alpha-beta T cell morphology	J:266693
	decreased CD4-positive, alpha-beta T cell number	J:266693
Nup210^enuI476T/Nup210^{tm1a(EUCOMM)Hmgu} involves: 129S1/Sv * 129X1/SvJ * C57BL/6N	decreased CD4-positive, alpha-beta T cell number	J:266693
Nup210^tm1.1Mdan/Nup210^tm1.1Mdan B6.Cg-Nup210^tm1.1Mdan	abnormal CD4-positive, alpha-beta T cell number	J:282451
	abnormal CD4-positive, alpha-beta T cell physiology	J:282451
	abnormal lymphocyte morphology	J:282451
	abnormal T cell activation	J:282451
	decreased CD4-positive, alpha-beta T cell number	J:282451
	decreased leukocyte cell number	J:282451
	normal hematopoietic system phenotype	J:282451
	increased effector memory T-helper cell number	J:282451
Nup210^{tm1b(EUCOMM)Hmgu}/Nup210^{tm1b(EUCOMM)Hmgu} involves: C57BL/6N	decreased alpha-beta T cell number	J:266693
	decreased CD4-positive, alpha-beta T cell number	J:266693
	decreased CD8-positive, alpha-beta T cell number	J:266693
	decreased T cell number	J:266693
	normal immune system phenotype	J:266693
	increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	J:266693
	increased CD8-positive, alpha-beta T cell number	J:266693
	increased central memory CD8 positive, alpha-beta T cell number	J:266693
	increased T-helper 1 cell number	J:266693
Nup210^tm1Mdan/Nup210^tm1Mdan Tg(Cd4-cre/ERT2)11Gnri/0 involves: 129X1/SvJ * C57BL/6	abnormal CD4-positive, alpha-beta T cell physiology	J:282451

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24