Nup210 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nup210
nucleoporin 210
MGI:1859555

21 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nup210^em1(IMPC)Mbp/Nup210^em1(IMPC)Mbp C57BL/6NCrl-Nup210^em1(IMPC)Mbp/MbpMmucd	abnormal liver morphology	J:211773
	abnormal vitreous body morphology	J:211773
	cataract	J:211773
	small liver	J:211773
Nup210^enuI476T/Nup210^enuI476T involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal alpha-beta T cell morphology	J:266693
	decreased CD4-positive, alpha-beta T cell number	J:266693
Nup210^enuI476T/Nup210^{tm1a(EUCOMM)Hmgu} involves: 129S1/Sv * 129X1/SvJ * C57BL/6N	decreased CD4-positive, alpha-beta T cell number	J:266693
Nup210^tm1.1Mdan/Nup210^tm1.1Mdan B6.Cg-Nup210^tm1.1Mdan	abnormal CD4-positive, alpha-beta T cell number	J:282451
	abnormal CD4-positive, alpha-beta T cell physiology	J:282451
	abnormal lymphocyte morphology	J:282451
	abnormal T cell activation	J:282451
	decreased CD4-positive, alpha-beta T cell number	J:282451
	decreased leukocyte cell number	J:282451
	normal hematopoietic system phenotype	J:282451
	increased effector memory T-helper cell number	J:282451
Nup210^{tm1b(EUCOMM)Hmgu}/Nup210^{tm1b(EUCOMM)Hmgu} involves: C57BL/6N	decreased alpha-beta T cell number	J:266693
	decreased CD4-positive, alpha-beta T cell number	J:266693
	decreased CD8-positive, alpha-beta T cell number	J:266693
	decreased T cell number	J:266693
	normal immune system phenotype	J:266693
	increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	J:266693
	increased CD8-positive, alpha-beta T cell number	J:266693
	increased central memory CD8 positive, alpha-beta T cell number	J:266693
	increased T-helper 1 cell number	J:266693
Nup210^tm1Mdan/Nup210^tm1Mdan Tg(Cd4-cre/ERT2)11Gnri/0 involves: 129X1/SvJ * C57BL/6	abnormal CD4-positive, alpha-beta T cell physiology	J:282451

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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