Ftsj1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ftsj1
FtsJ RNA 2'-O-methyltransferase 1
MGI:1859648

25 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ftsj1^{Gt(RRD143)Byg}/Y chimera involves: 129P2/OlaHsd	no abnormal phenotype detected	J:160967
Ftsj1^{tm1b(EUCOMM)Wtsi}/Y C57BL/6N-Ftsj1^{tm1b(EUCOMM)Wtsi}/Bay	abnormal retina inner nuclear layer morphology	J:211773
	decreased circulating alanine transaminase level	J:211773
	decreased circulating aspartate transaminase level	J:211773
	decreased total retina thickness	J:211773
Ftsj1^{tm1b(EUCOMM)Wtsi}/Ftsj1^{tm1b(EUCOMM)Wtsi} C57BL/6N-Ftsj1^{tm1b(EUCOMM)Wtsi}/Bay	abnormal retina inner nuclear layer morphology	J:211773
	abnormal retina vasculature morphology	J:211773
	decreased circulating phosphate level	J:211773
	decreased total retina thickness	J:211773
	hyperactivity	J:211773
Ftsj1^tm1Tomik/Y Not Specified	abnormal dendritic mushroom spine morphology	J:328916
	abnormal dendritic spine morphology	J:328916
	abnormal dendritic thin spine morphology	J:328916
	abnormal postsynaptic density morphology	J:328916
	normal cardiovascular system phenotype	J:328916
	decreased body weight	J:328916
	decreased dendritic spine density	J:328916
	impaired contextual conditioning behavior	J:328916
	impaired cued conditioning behavior	J:328916
	impaired spatial learning	J:328916
	impaired synaptic plasticity	J:328916
	increased anxiety-related response	J:328916
	normal liver/biliary system phenotype	J:328916
	reduced long-term depression	J:328916
	reduced long-term potentiation	J:328916
	normal renal/urinary system phenotype	J:328916
	normal reproductive system phenotype	J:328916

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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