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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Atp8b1
ATPase, class I, type 8B, member 1
MGI:1859665
61 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Atp8b1em1(IMPC)Tcp/Atp8b1em1(IMPC)Tcp
C57BL/6NCrl-Atp8b1em1(IMPC)Tcp/Tcp 		abnormal auditory brainstem response J:211773
abnormal bone structure J:211773
abnormal epididymis morphology J:211773
abnormal eye morphology J:211773
abnormal liver morphology J:211773
abnormal optic disk morphology J:211773
abnormal pancreas morphology J:211773
abnormal retina blood vessel morphology J:211773
abnormal retina vasculature morphology J:211773
abnormal startle reflex J:211773
anophthalmia J:211773
cornea opacity J:211773
decreased bone mineral content J:211773
decreased bone mineral density J:211773
decreased circulating glucose level J:211773
decreased circulating HDL cholesterol level J:211773
decreased circulating triglyceride level J:211773
decreased erythrocyte cell number J:211773
decreased exploration in new environment J:211773
decreased fasting circulating glucose level J:211773
decreased grip strength J:211773
decreased heart rate J:211773
decreased heart weight J:211773
decreased hematocrit J:211773
decreased hemoglobin content J:211773
decreased mean corpuscular hemoglobin J:211773
decreased mean corpuscular volume J:211773
decreased prepulse inhibition J:211773
decreased startle reflex J:211773
decreased total body fat amount J:211773
enlarged kidney J:211773
enlarged spleen J:211773
enlarged urinary bladder J:211773
improved glucose tolerance J:211773
increased circulating alanine transaminase level J:211773
increased circulating alkaline phosphatase level J:211773
increased circulating aspartate transaminase level J:211773
increased circulating bilirubin level J:211773
increased circulating potassium level J:211773
increased grip strength J:211773
increased lean body mass J:211773
increased leukocyte cell number J:211773
long tibia J:211773
persistence of hyaloid vascular system J:211773
polycystic kidney J:211773
prolonged RR interval J:211773
small seminal vesicle J:211773
Atp8b1tm1Nbf/Atp8b1tm1Nbf
involves: 129S1/SvImJ * 129S4/SvJae 		abnormal bile salt level J:89817
abnormal bile secretion J:89817
abnormal liver physiology J:89817
enlarged liver J:89817
increased circulating aspartate transaminase level J:89817
increased circulating bilirubin level J:89817
increased susceptibility to weight loss J:89817
postnatal growth retardation J:89817
Atp8b1tm1Nbf/Atp8b1tm1Nbf
involves: 129S4/SvJae 		abnormal cochlea morphology J:150079
abnormal cochlear ganglion morphology J:150079
abnormal outer hair cell stereociliary bundle morphology J:150079
cochlear inner hair cell degeneration J:150079
cochlear outer hair cell degeneration J:150079
degeneration of organ of Corti supporting cells J:150079
increased or absent threshold for auditory brainstem response J:150079
organ of Corti degeneration J:150079
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory