Cdc20 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cdc20
cell division cycle 20
MGI:1859866

38 phenotypes from 6 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cdc20^Gt(XE368)Byg/Cdc20^Gt(XE368)Byg involves: 129P2/OlaHsd * C57BL/6	abnormal chromosome morphology	J:121535
	embryonic lethality before implantation, incomplete penetrance	J:121535
	embryonic lethality between implantation and somite formation, complete penetrance	J:121535
Cdc20^Gt(XE368)Byg/Cdc20^tm1Jvd involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6	abnormal female meiosis	J:165500
	abnormal male germ cell morphology	J:165500
	abnormal oocyte morphology	J:165500
	aneuploidy	J:165500
	female infertility	J:165500
	maternal effect	J:165500
	reduced female fertility	J:165500
	normal reproductive system phenotype	J:165500
Cdc20^{tm1.1(KOMP)Vlcg}/Cdc20⁺ B6N(Cg)-Cdc20^{tm1.1(KOMP)Vlcg}/J	decreased circulating glucose level	J:211773
	improved glucose tolerance	J:211773
	increased circulating glucose level	J:211773
	increased fasting circulating glucose level	J:211773
	increased grip strength	J:211773
	increased heart weight	J:211773
Cdc20^{tm1.1(KOMP)Vlcg}/Cdc20^{tm1.1(KOMP)Vlcg} B6N(Cg)-Cdc20^{tm1.1(KOMP)Vlcg}/J	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	preweaning lethality, complete penetrance	J:211773
Cdc20^tm1.1Mama/Cdc20^tm1.2Mama Polr2a^{tm1(cre/ERT2)Bbd}/Polr2a⁺ involves: 129/Sv * BALB/cJ * C57BL/6 * CD-1 * SJL	abnormal epidermis stratum basale morphology	J:167609
	abnormal intestinal epithelium morphology	J:167609
	abnormal mitosis	J:167609
	decreased cell proliferation	J:167609
	decreased tumor growth/size	J:167609
	delayed hair regrowth	J:167609
	premature death	J:167609
	tumor regression	J:167609
	weight loss	J:167609
Cdc20^tm1.1Pzg/Cdc20⁺ involves: 129S7/SvEvBrd * C57BL/6	aneuploidy	J:150421
	increased hepatoma incidence	J:150421
	increased lymphoma incidence	J:150421
	increased tumor incidence	J:150421
Cdc20^tm1.1Pzg/Cdc20^tm1.1Pzg involves: 129S7/SvEvBrd * C57BL/6	abnormal cell death	J:150421
	abnormal mitosis	J:150421
	aneuploidy	J:150421
	decreased cell proliferation	J:150421
	decreased embryo size	J:150421
	embryonic lethality during organogenesis, complete penetrance	J:150421
	increased embryonic tissue cell apoptosis	J:150421
Cdc20^tm1.2Mama/Cdc20^tm1.2Mama involves: 129/Sv * BALB/cJ * C57BL/6 * CD-1 * SJL	embryonic lethality before implantation, complete penetrance	J:167609
	failure of zygotic cell division	J:167609
Cdc20^tm1Jvd/Cdc20^tm1Jvd involves: 129S6/SvEvTac * C57BL/6	normal reproductive system phenotype	J:165500

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24