Ppt2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ppt2
palmitoyl-protein thioesterase 2
MGI:1860075

32 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ppt2^tm1Hof/Ppt2^tm1Hof involves: 129S6/SvEvTac * C57BL/6J	abnormal bone marrow cell morphology/development	J:86202
	abnormal brain morphology	J:72931, J:86202
	abnormal cerebellar granule layer morphology	J:86202
	abnormal cerebellum white matter morphology	J:86202
	abnormal cerebral cortex morphology	J:86202
	abnormal exocrine pancreas morphology	J:86202
	abnormal gastric gland morphology	J:86202
	abnormal liver morphology	J:86202
	abnormal pancreas morphology	J:86202
	abnormal pancreatic acinar cell zymogen granule morphology	J:86202
	abnormal pyloric gastric gland morphology	J:86202
	abnormal retina pigment epithelium morphology	J:86202
	abnormal spleen morphology	J:86202
	abnormal testis interstitial tissue morphology	J:86202
	abnormal urinary bladder urothelium morphology	J:86202
	ataxia	J:86202
	decreased brain weight	J:86202
	decreased spleen B cell follicle number	J:86202
	enlarged liver	J:86202
	enlarged pancreas	J:86202
	enlarged spleen	J:86202
	extramedullary hematopoiesis	J:86202
	normal hematopoietic system phenotype	J:86202
	increased macrophage cell number	J:86202
	increased neuron apoptosis	J:86202
	increased spleen weight	J:86202
	jerky movement	J:72931, J:86202
	limb grasping	J:86202
	lipofuscinosis	J:86202
	muscle spasm	J:86202
	premature death	J:72931, J:86202
Ppt2^{tm2b(KOMP)Wtsi}/Ppt2^{tm2b(KOMP)Wtsi} C57BL/6N-Ppt2^{tm2b(KOMP)Wtsi}/H	increased blood urea nitrogen level	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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