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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Npffr2
neuropeptide FF receptor 2
MGI:1860130
34 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Npffr2tm1.1Hhzg/Npffr2tm1.1Hhzg
involves: C57BL/6 		abnormal adaptive thermogenesis J:267918
abnormal brown adipose tissue thermogenesis J:267918
normal behavior/neurological phenotype J:267918
decreased body weight J:267918
decreased energy expenditure J:267918
decreased food intake J:267918
decreased inguinal fat pad weight J:267918
decreased locomotor activity J:267918
decreased mesenteric fat pad weight J:267918
decreased respiratory quotient J:267918
decreased retroperitoneal fat pad weight J:267918
decreased white adipose tissue amount J:267918
hyperactivity J:267918
increased bone trabecula number J:267918
increased circulating insulin level J:267918
increased circulating leptin level J:267918
increased compact bone thickness J:267918
increased compact bone volume J:267918
increased energy expenditure J:267918
increased epididymal fat pad weight J:267918
increased inguinal fat pad weight J:267918
increased litter size J:267918
increased mesenteric fat pad weight J:267918
increased retroperitoneal fat pad weight J:267918
increased susceptibility to diet-induced obesity J:267918
increased trabecular bone mass J:267918
increased trabecular bone thickness J:267918
increased white adipose tissue amount J:267918
normal nervous system phenotype J:267918
short femur J:267918
Npffr2tm1.2Ics/Npffr2tm1.2Ics
involves: C57BL/6N 		abnormal macrophage activation involved in immune response J:245025
decreased macrophage cell number J:245025
decreased macrophage proliferation J:245025
normal homeostasis/metabolism phenotype J:245025
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory