Psmg1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Psmg1
proteasome (prosome, macropain) assembly chaperone 1
MGI:1860263

31 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Psmg1^tm1.1Smta/Psmg1^tm1.1Smta B6.Cg-Psmg1^tm1.1Smta	no abnormal phenotype detected	J:162790
Psmg1^tm1.1Smta/Psmg1^tm1.1Smta Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: C57BL/6 * CBA * DBA	abnormal hepatic cord morphology	J:162790
	abnormal hepatocyte morphology	J:162790
	abnormal hepatocyte physiology	J:162790
	abnormal liver sinusoid morphology	J:162790
	normal mortality/aging	J:162790
Psmg1^tm1.1Smta/Psmg1^tm1.1Smta Tg(Nes-cre)1Kln/0 involves: C57BL/6 * CBA * SJL	abnormal cerebellum development	J:162790
	abnormal cerebellum morphology	J:162790
	abnormal cerebral hemisphere morphology	J:162790
	ataxia	J:162790
	decreased cerebellar granule cell precursor proliferation	J:162790
	decreased dentate gyrus size	J:162790
	limb grasping	J:162790
	postnatal growth retardation	J:162790
	postnatal lethality, complete penetrance	J:162790
	small hippocampus	J:162790
	thin cerebral cortex	J:162790
	tremors	J:162790
Psmg1^tm1.2Smta/Psmg1^tm1.2Smta involves: C57BL/6 * CBA * FVB/N	abnormal embryo development	J:162790
	embryonic lethality between implantation and somite formation, complete penetrance	J:162790
Psmg1^{tm1b(KOMP)Wtsi}/Psmg1⁺ C57BL/6N-Psmg1^{tm1b(KOMP)Wtsi}/Bay	abnormal embryo size	J:211773
	abnormal embryo turning	J:211773
	abnormal neural tube closure	J:211773
	abnormal neural tube morphology	J:211773
	abnormal pharyngeal arch morphology	J:211773
	abnormal visceral yolk sac morphology	J:211773
	cornea opacity	J:211773
	embryonic growth retardation	J:211773
	hyperactivity	J:211773
Psmg1^{tm1b(KOMP)Wtsi}/Psmg1^{tm1b(KOMP)Wtsi} C57BL/6N-Psmg1^{tm1b(KOMP)Wtsi}/Bay	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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