Sfrp5 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sfrp5
secreted frizzled-related sequence protein 5
MGI:1860298

16 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Dkk1^tm1Lmgd/Dkk1^tm1Lmgd Sfrp5^tm1Shwl/Sfrp5^tm1Shwl involves: 129 * CD-1	abnormal anterior head development	J:117057
	normal embryo phenotype	J:117057
	perinatal lethality, complete penetrance	J:117057
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2⁺ Sfrp5^tm1Aksh/Sfrp5^tm1Aksh Vangl2^Lp/Vangl2⁺ involves: 129 * A * C57BL/6 * LPT/LeJ	spina bifida	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5⁺ involves: 129 * C57BL/6	abnormal rostral-caudal axis patterning	J:135313
	abnormal somite development	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5⁺ Vangl2^Lp/Vangl2⁺ involves: 129 * A * C57BL/6 * LPT/LeJ	abnormal rostral-caudal body axis extension	J:135313
	abnormal somite development	J:135313
	craniorachischisis	J:135313
	open neural tube	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5^tm1Aksh involves: 129 * C57BL/6	abnormal rostral-caudal axis patterning	J:135313
	decreased somite size	J:135313
	embryonic growth retardation	J:135313
	embryonic lethality, complete penetrance	J:135313
	fused somites	J:135313
	incomplete somite formation	J:135313
	open neural tube	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp5^tm1Aksh/Sfrp5^tm1Aksh Vangl2^Lp/Vangl2⁺ involves: 129 * A * C57BL/6 * LPT/LeJ	spina bifida	J:135313
Sfrp2^C50F/Sfrp2^C50F Sfrp5^Q27stop/Sfrp5^Q27stop involves: BALB/c * C3H/HeH	abnormal seminiferous tubule morphology	J:119228
	kinked tail	J:119228

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24