Sfrp5 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Sfrp5
secreted frizzled-related sequence protein 5
MGI:1860298

16 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Dkk1^tm1Lmgd/Dkk1^tm1Lmgd Sfrp5^tm1Shwl/Sfrp5^tm1Shwl involves: 129 * CD-1	abnormal anterior head development	J:117057
	normal embryo phenotype	J:117057
	perinatal lethality, complete penetrance	J:117057
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2⁺ Sfrp5^tm1Aksh/Sfrp5^tm1Aksh Vangl2^Lp/Vangl2⁺ involves: 129 * A * C57BL/6 * LPT/LeJ	spina bifida	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5⁺ involves: 129 * C57BL/6	abnormal rostral-caudal axis patterning	J:135313
	abnormal somite development	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5⁺ Vangl2^Lp/Vangl2⁺ involves: 129 * A * C57BL/6 * LPT/LeJ	abnormal rostral-caudal body axis extension	J:135313
	abnormal somite development	J:135313
	craniorachischisis	J:135313
	open neural tube	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp2^tm1Aksh/Sfrp2^tm1Aksh Sfrp5^tm1Aksh/Sfrp5^tm1Aksh involves: 129 * C57BL/6	abnormal rostral-caudal axis patterning	J:135313
	decreased somite size	J:135313
	embryonic growth retardation	J:135313
	embryonic lethality, complete penetrance	J:135313
	fused somites	J:135313
	incomplete somite formation	J:135313
	open neural tube	J:135313
Sfrp1^tm1Aksh/Sfrp1^tm1Aksh Sfrp5^tm1Aksh/Sfrp5^tm1Aksh Vangl2^Lp/Vangl2⁺ involves: 129 * A * C57BL/6 * LPT/LeJ	spina bifida	J:135313
Sfrp2^C50F/Sfrp2^C50F Sfrp5^Q27stop/Sfrp5^Q27stop involves: BALB/c * C3H/HeH	abnormal seminiferous tubule morphology	J:119228
	kinked tail	J:119228

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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