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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ptbp2
polypyrimidine tract binding protein 2
MGI:1860489
29 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ptbp2em1(IMPC)Hmgu/Ptbp2+
C57BL/6NCrl-Ptbp2em1(IMPC)Hmgu/Ieg 		abnormal tooth morphology J:211773
abnormal vibrissa morphology J:211773
decreased total retina thickness J:211773
Ptbp2em1(IMPC)Hmgu/Ptbp2em1(IMPC)Hmgu
C57BL/6NCrl-Ptbp2em1(IMPC)Hmgu/Ieg 		preweaning lethality, complete penetrance J:211773
Ptbp2Gt(NPX210)Byg/Ptbp2Gt(NPX210)Byg
involves: 129P2/OlaHsd 		abnormal cortical ventricular zone morphology J:185949
abnormal neuron differentiation J:185949
decreased neuronal precursor cell number J:185949
neonatal lethality J:185949
premature neuronal precursor differentiation J:185949
Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk
Emx1tm1(cre)Ito/Emx1+
involves: 129P2/OlaHsd * 129S2/SvPas 		abnormal mitral cell morphology J:207976
abnormal olfactory bulb layer morphology J:207976
absent corpus callosum J:207976
decreased body size J:207976
enlarged lateral ventricles J:207976
neurodegeneration J:207976
neuron degeneration J:207976
postnatal growth retardation J:207976
postnatal lethality, complete penetrance J:207976
slow postnatal weight gain J:207976
small hippocampus J:207976
thin cerebral cortex J:207976
Ptbp2tm1.1Dblk/Ptbp2tm1.1Dblk
Tg(Nes-cre)1Kln/0
involves: 129S2/SvPas * C57BL/6 * SJL 		abnormal brain commissure morphology J:207976
abnormal brain internal capsule morphology J:207976
abnormal brain white matter morphology J:207976
abnormal olfactory tract morphology J:207976
cyanosis J:207976
neonatal lethality, complete penetrance J:207976
Ptbp2tm1.1Rbd/Ptbp2tm1.1Rbd
Not Specified 		abnormal cortical ventricular zone morphology J:185949
abnormal neuron differentiation J:185949
decreased neuronal precursor cell number J:185949
neonatal lethality, complete penetrance J:185949
premature neuronal precursor differentiation J:185949
Ptbp2tm1.2Dblk/Ptbp2tm1.2Dblk
involves: 129S2/SvPas * FVB/N 		neonatal lethality, complete penetrance J:207976
neurodegeneration J:207976
paralysis J:207976
respiratory failure J:207976
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory