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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Abcb10
ATP-binding cassette, sub-family B member 10
MGI:1860508
24 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Abcb10tm1.1Tafu/Abcb10tm1.2Tafu
Tg(Mx1-cre)1Cgn/0
involves: C57BL/6J * C57BL/6NCrlj * CBA/J * CBA/JNCrlJ 		abnormal erythropoiesis J:223428
abnormal hemoglobin J:223428
abnormal iron level J:223428
abnormal mitochondrial morphology J:223428
decreased erythrocyte cell number J:223428
decreased hemoglobin content J:223428
decreased mean corpuscular hemoglobin concentration J:223428
decreased mean corpuscular volume J:223428
hypochromic microcytic anemia J:223428
reticulocytosis J:223428
Abcb10tm1.2Tafu/Abcb10tm1.2Tafu
involves: C57BL/6NCrlj * CBA/JNCrlj 		abnormal blood cell morphology J:223428
abnormal embryonic hematopoiesis J:223428
abnormal hemoglobin J:223428
abnormal hepatocyte morphology J:223428
abnormal iron level J:223428
abnormal liver morphology J:223428
abnormal liver physiology J:223428
embryonic lethality during organogenesis, complete penetrance J:223428
oxidative stress J:223428
pallor J:223428
Abcb10tm1Lex/Abcb10+
involves: 129S/SvEvBrd * C57BL/6 		abnormal mitochondrial physiology J:189396
normal cardiovascular system phenotype J:189396
decreased systemic arterial systolic blood pressure J:189396
increased response of heart to induced stress J:189396
increased systemic arterial diastolic blood pressure J:189396
oxidative stress J:189396
Abcb10tm1Lex/Abcb10tm1Lex
involves: 129S/SvEvBrd * C57BL/6 		embryonic lethality, complete penetrance J:189396
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory