Heyl Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Heyl
hairy/enhancer-of-split related with YRPW motif-like
MGI:1860511

20 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Hey1^tm1Gess/Hey1^tm1Gess Heyl^tm1.2Abmu/Heyl⁺ involves: 129 * C57BL/6 * FVB/N	increased sensory neuron number	J:153555
Hey1^tm1Gess/Hey1^tm1Gess Heyl^tm1.2Abmu/Heyl^tm1.2Abmu involves: 129 * C57BL/6 * FVB/N	normal nervous system phenotype	J:153555
Hey1^tm1Gess/Hey1^tm1Gess Heyl^tm1Gess/Heyl^tm1Gess either: B6.129-Hey1^tm1Gess Heyl^tm1Gess or (involves: 129 * C57BL/6)	abnormal atrioventricular cushion morphology	J:133699
	abnormal atrioventricular valve morphology	J:133699
	abnormal cardiac epithelial to mesenchymal transition	J:133699
	abnormal conotruncal ridge morphology	J:133699
	increased heart ventricle size	J:133699
	perimembraneous ventricular septal defect	J:133699
	postnatal lethality, incomplete penetrance	J:133699
	pulmonary valve stenosis	J:133699
	thick pulmonary valve	J:133699
Hey1^tm1Kkb/Hey1^tm1Kkb Heyl^tm1Kkb/Heyl^tm1Kkb B6.Cg-Hey1^tm1Kkb Heyl^tm1Kkb	abnormal skeletal muscle morphology	J:178310
	abnormal skeletal muscle satellite cell proliferation	J:178310
	decreased body size	J:178310
	decreased body weight	J:178310
	decreased muscle weight	J:178310
	decreased satellite cell number	J:178310
	decreased skeletal muscle fiber number	J:178310
	decreased skeletal muscle fiber size	J:178310
	impaired skeletal muscle regeneration	J:178310
	postnatal lethality, incomplete penetrance	J:178310
Hey1^tm1Kkb/Hey1^tm1Kkb Heyl^tm1Kkb/Heyl^tm1Kkb involves: 129S7/SvEvBrd * C57BL/6	postnatal lethality, incomplete penetrance	J:178310

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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