Extl3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Extl3
exostosin-like glycosyltransferase 3
MGI:1860765

22 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Extl3^em1(IMPC)Mbp/Extl3⁺ C57BL/6N-Extl3^em1(IMPC)Mbp/MbpMmucd	abnormal eye morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal liver morphology	J:211773
	abnormal prostate gland morphology	J:211773
	abnormal skin morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	enlarged liver	J:211773
	enlarged spleen	J:211773
	microphthalmia	J:211773
	small kidney	J:211773
	small testis	J:211773
Extl3^em1(IMPC)Mbp/Extl3^em1(IMPC)Mbp C57BL/6N-Extl3^em1(IMPC)Mbp/MbpMmucd	embryonic lethality prior to organogenesis	J:211773
	preweaning lethality, complete penetrance	J:211773
Extl3^tm1.1Okam/Extl3^tm1.1Okam involves: 129P2/OlaHsd * ICR	embryonic lethality, complete penetrance	J:148348
Extl3^tm1.1Okam/Extl3^tm1Okam Tg(Ins2-cre)#Okam/0 involves: 129P2/OlaHsd * ICR	decreased cell proliferation	J:148348
	decreased circulating insulin level	J:148348
	decreased insulin secretion	J:148348
	decreased pancreatic beta cell mass	J:148348
	decreased pancreatic beta cell number	J:148348
	disorganized pancreatic islets	J:148348
	impaired glucose tolerance	J:148348

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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