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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Clec4e
C-type lectin domain family 4, member e
MGI:1861232
23 phenotypes from 2 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Clec4etm1.1Cfg/Clec4etm1.1Cfg
B6.Cg-Clec4etm1.1Cfg 		abnormal heart morphology J:136334
abnormal heart valve morphology J:136334
abnormal macrophage physiology J:136334
decreased lymphocyte cell number J:136334
decreased monocyte cell number J:136334
decreased neutrophil cell number J:136334
decreased tumor necrosis factor secretion J:136334
increased susceptibility to fungal infection J:136334
Clec4etm1Tks/Clec4etm1Tks
involves: 129S1/Sv * 129X1/SvJ 		abnormal chemokine secretion J:203159
abnormal immune serum protein physiology J:203159
abnormal interferon-gamma secretion J:203159
abnormal interleukin-17 secretion J:203159
abnormal response to infection J:203159
decreased circulating interleukin-17 level J:203159
decreased dendritic cell number J:203159
decreased IgG level J:203159
decreased physiological sensitivity to xenobiotic J:203159
decreased susceptibility to experimental autoimmune encephalomyelitis J:203159
decreased susceptibility to type IV hypersensitivity reaction J:203159
decreased susceptibility to xenobiotic induced morbidity/mortality J:203159
decreased tumor necrosis factor secretion J:203159
Clec4etm1Tks/Clec4etm1Tks
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal chemokine secretion J:172959
decreased interleukin-6 secretion J:172959
decreased interleukin-10 secretion J:172959
decreased neutrophil cell number J:172959
decreased susceptibility to fungal infection J:172959
decreased tumor necrosis factor secretion J:172959
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory