About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Clec4e
C-type lectin domain family 4, member e
MGI:1861232
23 phenotypes from 2 alleles in 3 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Clec4etm1.1Cfg/Clec4etm1.1Cfg
B6.Cg-Clec4etm1.1Cfg 		abnormal heart morphology J:136334
abnormal heart valve morphology J:136334
abnormal macrophage physiology J:136334
decreased lymphocyte cell number J:136334
decreased monocyte cell number J:136334
decreased neutrophil cell number J:136334
decreased tumor necrosis factor secretion J:136334
increased susceptibility to fungal infection J:136334
Clec4etm1Tks/Clec4etm1Tks
involves: 129S1/Sv * 129X1/SvJ 		abnormal chemokine secretion J:203159
abnormal immune serum protein physiology J:203159
abnormal interferon-gamma secretion J:203159
abnormal interleukin-17 secretion J:203159
abnormal response to infection J:203159
decreased circulating interleukin-17 level J:203159
decreased dendritic cell number J:203159
decreased IgG level J:203159
decreased physiological sensitivity to xenobiotic J:203159
decreased susceptibility to experimental autoimmune encephalomyelitis J:203159
decreased susceptibility to type IV hypersensitivity reaction J:203159
decreased susceptibility to xenobiotic induced morbidity/mortality J:203159
decreased tumor necrosis factor secretion J:203159
Clec4etm1Tks/Clec4etm1Tks
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal chemokine secretion J:172959
decreased interleukin-6 secretion J:172959
decreased interleukin-10 secretion J:172959
decreased neutrophil cell number J:172959
decreased susceptibility to fungal infection J:172959
decreased tumor necrosis factor secretion J:172959
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory