Fntb Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fntb
farnesyltransferase, CAAX box, beta
MGI:1861305

13 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Fntb^tm1.1Mbrg/Fntb^tm1.1Mbrg Pggt1b^tm1Mbrg/Pggt1b^tm1Mbrg involves: 129P2/OlaHsd * C57BL/6	increased fibroblast apoptosis	J:158937
Fntb^tm1.1Mbrg/Fntb^tm1.1Mbrg Pggt1b^tm1Mbrg/Pggt1b^tm1Mbrg Tg(KRT14-cre)1Amc/? involves: 129P2/OlaHsd * C57BL/6 * CBA	abnormal skin physiology	J:158528
	decreased hair follicle number	J:158528
	thin epidermis	J:158528
Fntb^tm1.1Mbrg/Fntb^tm1.2Mbrg Kras^tm4Tyj/Kras⁺ involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N	abnormal cell cycle	J:158937
Fntb^tm1.1Mbrg/Fntb^tm1.2Mbrg Kras^tm4Tyj/Kras⁺ Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N	decreased tumor growth/size	J:158937
	increased lung tumor incidence	J:158937
	increased lung weight	J:158937
	premature death	J:158937
Fntb^tm1.1Mbrg/Fntb^tm1.2Mbrg Kras^tm4Tyj/Kras⁺ Pggt1b^tm1Mbrg/Pggt1b^tm1.1Mbrg involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N	abnormal lung epithelium morphology	J:158937
	decreased tumor growth/size	J:158937
	increased lung adenoma incidence	J:158937
	increased lung carcinoma incidence	J:158937
	increased lung tumor incidence	J:158937
Fntb^tm1.1Mbrg/Fntb^tm1.2Mbrg Kras^tm4Tyj/Kras⁺ Pggt1b^tm1Mbrg/Pggt1b^tm1.1Mbrg Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N	decreased tumor growth/size	J:158937
	increased lung tumor incidence	J:158937
	premature death	J:158937
Fntb^tm1Bbd/Fntb^tm1Bbd Kras^tm1Bbd/Kras⁺ Polr2a^{tm1(cre/ERT2)Bbd}/Polr2a^{tm1(cre/ERT2)Bbd} involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	increased lung adenocarcinoma incidence	J:98944
	increased lung adenoma incidence	J:98944

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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