Gcm2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gcm2
glial cells missing homolog 2
MGI:1861438

21 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gcm2^tm1.1Malx/Gcm2^tm1.1Malx C57BL/6N-Gcm2^tm1.1Malx	no abnormal phenotype detected	J:213334
Gcm2^tm1.2Malx/Gcm2^tm1.2Malx involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6N	decreased circulating calcium level	J:213334
	decreased circulating parathyroid hormone level	J:213334
	increased circulating phosphate level	J:213334
	lethality, incomplete penetrance	J:213334
	parathyroid hypoplasia	J:213334
Gcm2^tm1Hoso/Gcm2^tm1Hoso either: (involves: 129X1/SvJ * C57BL/6) or (involves: 129X1/SvJ * CD-1)	abnormal DNA methylation	J:175891
	abnormal neuron differentiation	J:175891
	decreased brain size	J:175891
	embryonic lethality during organogenesis, incomplete penetrance	J:175891
	incomplete rostral neuropore closure	J:175891
Gcm2^tm1Kry/Gcm2^tm1Kry involves: 129S7/SvEvBrd	abnormal bone ossification	J:63291
	abnormal trabecular bone morphology	J:63291
	absent parathyroid glands	J:63291
	decreased activity of parathyroid	J:63291
	decreased circulating calcium level	J:63291, J:78067
	decreased circulating phosphate level	J:63291
	increased bone mass	J:63291
	increased urine calcium level	J:63291
	perinatal lethality, incomplete penetrance	J:63291
Gcm2^tm1Kry/Gcm2^tm1Kry involves: 129S7/SvEvBrd * C57BL/6J	abnormal parathyroid gland development	J:121311
	abnormal third pharyngeal arch morphology	J:121311
	absent parathyroid glands	J:121311

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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