Dynll1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dynll1
dynein light chain LC8-type 1
MGI:1861457

24 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cd79a^tm1(cre)Reth/Cd79a⁺ Dynll1^tm1.1Jhh/Dynll1^tm1.1Jhh B6.Cg-Dynll1^tm1.1Jhh Cd79a^tm1(Cre)Reth	abnormal B cell morphology	J:230105
	decreased immature B cell number	J:230105
	decreased mature B cell number	J:230105
	decreased pre-B cell number	J:230105
Dynll1^{Gt(EUCE0287d04)Hmgu}/Dynll1^{Gt(EUCE0287d04)Hmgu} involves: 129P2/OlaHsd	abnormal cardiac outflow tract development	J:217609
	abnormal embryonic neuroepithelium primary cilium morphology	J:217609
	abnormal primary cilium morphology	J:217609
	absent lungs	J:217609
	coloboma	J:217609
	decreased embryonic cilium length	J:217609
	dextrocardia	J:217609
	edema	J:217609
	exencephaly	J:217609
	interrupted aortic arch	J:217609
	left pulmonary isomerism	J:217609
	microphthalmia	J:217609
	right-sided stomach	J:217609
	small lung	J:217609
Dynll1^{tm1(KOMP)Wtsi}/Dynll1⁺ C57BL/6N-Dynll1^{tm1(KOMP)Wtsi}/Wtsi	decreased circulating fructosamine level	J:211773
	decreased circulating glucose level	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating bilirubin level	J:211773
Dynll1^{tm1(KOMP)Wtsi}/Dynll1^{tm1(KOMP)Wtsi} C57BL/6N-Dynll1^{tm1(KOMP)Wtsi}/Wtsi	preweaning lethality, complete penetrance	J:211773
Dynll1^tm1.1Jhh/Dynll1^tm1.1Jhh C57BL/6NTac-Dynll1^tm1.1Jhh	no abnormal phenotype detected	J:230105

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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