Aldh1a3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
MGI:1861722

23 phenotypes from 4 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Aldh1a3^tm1.1Pcn/Aldh1a3^tm1.1Pcn involves: 129/Sv * C57BL/6	abnormal nasal cavity morphology	J:90261
	abnormal periocular mesenchyme morphology	J:102847
	absent Harderian gland	J:90261
	absent maxillary sinus	J:90261
	absent nasolacrimal duct	J:90261
	choanal atresia	J:90261
	cyanosis	J:90261
	decreased periocular mesenchyme apoptosis	J:102847
	decreased ventral retina size	J:90261
	ethmoturbinate hypoplasia	J:90261
	neonatal lethality, complete penetrance	J:90261
	persistent hyperplastic primary vitreous	J:90261
	persistent nasal fins	J:90261
	respiratory distress	J:90261
	ventral rotation of lens	J:90261
Aldh1a3^{tm1b(KOMP)Wtsi}/Aldh1a3⁺ B6N(Cg)-Aldh1a3^{tm1b(KOMP)Wtsi}/J	hyperactivity	J:211773
	increased circulating alkaline phosphatase level	J:211773
Aldh1a3^{tm1b(KOMP)Wtsi}/Aldh1a3^{tm1b(KOMP)Wtsi} B6N(Cg)-Aldh1a3^{tm1b(KOMP)Wtsi}/J	microphthalmia	J:211773
	preweaning lethality, complete penetrance	J:211773
Aldh1a3^tm1Gdu/Aldh1a3^tm1Gdu involves: C57BL/6	abnormal vitreous body morphology	J:108515
	increased total retina thickness	J:108515
	neonatal lethality, complete penetrance	J:119190
	persistent hyperplastic primary vitreous	J:108515
Aldh1a3^tm1Gdu/Aldh1a3^tm1Gdu involves: C57BL/6 * Swiss Webster	normal renal/urinary system phenotype	J:157254
Aldh1a3^tm1Pcn/Aldh1a3^tm1Pcn involves: 129/Sv * C57BL/6	no abnormal phenotype detected	J:90261

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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