Aldh1a3 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
MGI:1861722

23 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Aldh1a1^tm1.1Ngb/Aldh1a1^tm1.1Ngb Aldh1a3^tm1.1Pcn/Aldh1a3^tm1.1Pcn involves: 129/Sv * C57BL/6 * SJL	abnormal conjunctival sac morphology	J:102847
	abnormal cornea stroma development	J:102847
	abnormal eyelid development	J:102847
	abnormal nose morphology	J:102847
	absent Harderian gland	J:102847
	absent iris stroma	J:102847
	absent sclera	J:102847
	decreased periocular mesenchyme apoptosis	J:102847
	decreased ventral retina size	J:102847
	neonatal lethality, complete penetrance	J:102847
	persistent hyperplastic primary vitreous	J:102847
	respiratory distress	J:102847
	ventral rotation of lens	J:102847
Aldh1a1^tm1Gdu/Aldh1a1^tm1Gdu Aldh1a2^tm1Gdu/Aldh1a2^tm1Gdu Aldh1a3^tm1Gdu/Aldh1a3^tm1Gdu involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal optic cup morphology	J:108515
Aldh1a1^tm1Gdu/Aldh1a1^tm1Gdu Aldh1a3^tm1Gdu/Aldh1a3^tm1Gdu involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal periocular mesenchyme morphology	J:108515
	abnormal posterior eye segment morphology	J:108515
	abnormal vitreous body morphology	J:108515
	decreased periocular mesenchyme apoptosis	J:108515
	increased cornea stroma thickness	J:108515
	increased total retina thickness	J:108515
	persistent hyperplastic primary vitreous	J:108515
	thick eyelids	J:108515
Aldh1a2^tm1Gdu/Aldh1a2^tm1Gdu Aldh1a3^tm1Gdu/Aldh1a3^tm1Gdu involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal optic cup morphology	J:108515
Aldh1a2^tm1Gdu/Aldh1a2^tm1Gdu Aldh1a3^tm1Gdu/Aldh1a3^tm1Gdu involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * Swiss Webster	impaired branching involved in ureteric bud morphogenesis	J:157254
	renal hypoplasia	J:157254
Aldh1a3^tm1Gdu/Aldh1a3⁺ Chd7^{Gt(S20-7E1)Sor}/Chd7⁺ involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6J	abnormal semicircular canal morphology	J:314662
Aldh1a3^tm1Gdu/Aldh1a3^tm1Gdu Chd7^{Gt(S20-7E1)Sor}/Chd7⁺ involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6J	abnormal semicircular canal morphology	J:314662

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24