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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Gtf2ird1
general transcription factor II I repeat domain-containing 1
MGI:1861942
31 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+
involves: C57BL/6 * CBA 		abnormal hepatocyte morphology J:34434
increased hepatocellular carcinoma incidence J:34434, J:101128
increased liver adenoma incidence J:34434
increased liver tumor incidence J:101128
increased liver weight J:34434
Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+
involves: C57BL/6J * CBA/J 		abnormal circadian behavior J:190478
abnormal eating behavior J:190478
decreased body weight J:190478
impaired coordination J:190478
postnatal growth retardation J:190478
slow postnatal weight gain J:190478
Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+
Tg(MtTGFA)42Lmb/0
involves: C57BL/6 * CBA * CD-1 		abnormal hepatocyte morphology J:34434
increased hepatocellular carcinoma incidence J:34434
increased hepatocyte apoptosis J:34434
increased hepatocyte karyomegaly J:34434
increased liver adenoma incidence J:34434
increased liver weight J:34434
multifocal hepatic necrosis J:34434
Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1+
Tg(Alb-E2F1)8Sst/0
involves: C57BL/6 * CBA 		increased hepatocellular carcinoma incidence J:101128
increased liver tumor incidence J:101128
Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1Tg(Alb1-Myc)166.8Sst
involves: C57BL/6 * CBA 		abnormal mastication J:102709
asymmetric snout J:102709
decreased body weight J:102709
limb grasping J:102709
malocclusion J:102709
periorbital fullness J:102709
short snout J:102709
Gtf2ird1Tg(Alb1-Myc)166.8Sst/Gtf2ird1Tg(Alb1-Myc)166.8Sst
involves: C57BL/6J * CBA/J 		abnormal circadian behavior J:190478
abnormal eating behavior J:190478
abnormal fear/anxiety-related behavior J:190478
abnormal gait J:190478
abnormal jaw morphology J:190478
abnormal nest building behavior J:190478
abnormal response to new environment J:190478
decreased body weight J:190478
decreased grip strength J:190478
decreased vertical activity J:190478
impaired coordination J:190478
increased anxiety-related response J:190478
increased circulating corticosterone level J:190478
increased grooming behavior J:190478
increased response to stress-induced hyperthermia J:190478
limb grasping J:190478
periorbital fullness J:190478
postnatal growth retardation J:190478
short snout J:190478
slow postnatal weight gain J:190478
Gtf2ird1Tg(Alb1-Myc)166.8Sst/0
Tg(MtTGFA)42Lmb/0
involves: C57BL/6 * CBA * CD-1 		increased hepatocellular carcinoma incidence J:4527
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory