Tbx20 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Tbx20
T-box 20
MGI:1888496

47 phenotypes from 7 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tbx20^em1(IMPC)Mbp/Tbx20⁺ C57BL/6N-Tbx20^em1(IMPC)Mbp/MbpMmucd	abnormal placenta morphology	J:211773
	increased neutrophil cell number	J:211773
Tbx20^em1(IMPC)Mbp/Tbx20^em1(IMPC)Mbp C57BL/6N-Tbx20^em1(IMPC)Mbp/MbpMmucd	abnormal blood vessel morphology	J:211773
	abnormal embryo turning	J:211773
	abnormal forebrain development	J:211773
	abnormal heart looping	J:211773
	abnormal heart morphology	J:211773
	abnormal neural tube closure	J:211773
	abnormal neural tube morphology	J:211773
	abnormal optic vesicle formation	J:211773
	abnormal otic vesicle morphology	J:211773
	abnormal pharyngeal arch morphology	J:211773
	abnormal somite shape	J:211773
	abnormal visceral yolk sac morphology	J:211773
	abnormal vitelline vasculature morphology	J:211773
	hemorrhage	J:211773
	prenatal lethality prior to heart atrial septation	J:211773
	preweaning lethality, complete penetrance	J:211773
Tbx20^em1Ona/Tbx20^em1Ona involves: C57BL/6 * DBA	abnormal cardiac outflow tract development	J:288309
Tbx20^em1Ona/Tbx20^em1Ona involves: C57BL/6 * DBA	common ventricle	J:288309
Tbx20^tm1.1Rph/Tbx20⁺ involves: C57BL/6	decreased heart left ventricle muscle contractility	J:98489
	decreased heart left ventricle wall thickness	J:98489
	dilated cardiomyopathy	J:98489
	dilated heart left atrium	J:98489
	dilated heart left ventricle	J:98489
Tbx20^tm1.1Rph/Tbx20^tm1.1Rph involves: C57BL/6	abnormal body wall morphology	J:98489
	abnormal fetal cardiomyocyte proliferation	J:98489
	abnormal heart tube morphology	J:98489
	abnormal visceral yolk sac mesenchyme morphology	J:98489
	abnormal vitelline vascular remodeling	J:98489
	embryonic lethality during organogenesis, complete penetrance	J:98489
	failure of heart looping	J:98489
Tbx20^tm1.1Sev/Tbx20^tm1.1Sev involves: 129S6/SvEvTac * C57BL/6	abnormal fetal cardiomyocyte proliferation	J:98516
	abnormal heart tube morphology	J:98516
	embryonic growth arrest	J:98516
	embryonic lethality during organogenesis, complete penetrance	J:98516
	failure of heart looping	J:98516
	heart hypoplasia	J:98516
Tbx20^tm1.2Rph/Tbx20^tm1.2Rph B6.Cg-Tbx20^tm1.2Rph	no abnormal phenotype detected	J:101977
Tbx20^tm1Akis/Tbx20^tm1Akis involves: 129S1/SvImJ * NMRI	abnormal blood circulation	J:98806
	abnormal fetal cardiomyocyte proliferation	J:98806
	abnormal heart development	J:98806
	abnormal heart tube morphology	J:98806
	abnormal vascular development	J:98806
	edema	J:98806
	embryonic growth arrest	J:98806
	embryonic growth retardation	J:98806
	embryonic lethality during organogenesis, complete penetrance	J:98806
	failure of heart looping	J:98806
Tbx20^tm1Sev/Tbx20^tm1.1Sev Nfatc1^tm1.1(cre)Bz/Nfatc1⁺ involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Black Swiss	abnormal cardiovascular system physiology	J:198628
	abnormal heart valve morphology	J:198628
	aortic valve regurgitation	J:198628
	decreased atrioventricular cushion size	J:198628
	hemorrhage	J:198628
	lethality throughout fetal growth and development, complete penetrance	J:198628
	small atrioventricular valve	J:198628
	small semilunar valve	J:198628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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