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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Fzd2
frizzled class receptor 2
MGI:1888513
27 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dvl3tm1Awb/Dvl3+
Fzd2tm1.1Nat/Fzd2+
Fzd7tm1.1Nat/Fzd7tm1.1Nat
involves: 129 * C57BL/6 		abnormal heart morphology J:189062
ventricular septal defect J:189062
Fzd1tm1.1Nat/Fzd1+
Fzd2tm1.1Nat/Fzd2+
Vangl2Lp/Vangl2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * LPT/LeJ 		open neural tube J:165556
ventricular septal defect J:165556
Fzd1tm1.1Nat/Fzd1+
Fzd2tm1.1Nat/Fzd2tm1.1Nat
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal heart morphology J:165556
Fzd1tm1.1Nat/Fzd1tm1.1Nat
Fzd2tm1.1Nat/Fzd2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal heart morphology J:165556
cleft palate J:165556
Fzd1tm1.1Nat/Fzd1tm1.1Nat
Fzd2tm1.1Nat/Fzd2tm1.1Nat
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA 		abnormal cochlear hair cell morphology J:165556
abnormal cochlear hair cell number J:165556
abnormal heart morphology J:165556
abnormal mouth morphology J:165556
abnormal orientation of outer hair cell stereociliary bundles J:165556
abnormal palate development J:165556
cleft palate J:165556
cyanosis J:165556
double outlet right ventricle J:165556
normal embryo phenotype J:165556
failure of palatal shelf elevation J:165556
overriding aortic valve J:165556
palatal shelves fail to meet at midline J:165556
short mandible J:165556
ventricular septal defect J:165556
Fzd2tm1.1Nat/Fzd2+
Vangl2Lp/Vangl2+
involves: 129 * C57BL/6 * LPT/LeJ 		abnormal heart morphology J:189062
ventricular septal defect J:189062
Fzd2tm1.1Nat/Fzd2+
Fzd7tm1.1Nat/Fzd7tm1.1Nat
involves: 129 * C57BL/6 		abnormal heart morphology J:189062
normal craniofacial phenotype J:189062
double outlet right ventricle J:189062
postnatal lethality, incomplete penetrance J:189062
ventricular septal defect J:189062
Fzd2tm1.1Nat/Fzd2+
Fzd7tm1.1Nat/Fzd7tm1.1Nat
involves: 129 * C57BL/6 * LPT/LeJ 		cleft palate J:189062
Fzd2tm1.1Nat/Fzd2+
Fzd7tm1.1Nat/Fzd7tm1.1Nat
Vangl2Lp/Vangl2+
involves: 129 * C57BL/6 * LPT/LeJ 		abnormal heart morphology J:189062
cleft palate J:189062
ventricular septal defect J:189062
Fzd2tm1.1Nat/Fzd2+
Fzd7tm1.1Nat/Fzd7tm1.1Nat
Wnt3atm1Amc/Wnt3a+
involves: 129 * C57BL/6 		abnormal heart morphology J:189062
cleft palate J:189062
ventricular septal defect J:189062
Fzd2tm1.1Nat/Fzd2+
Fzd7tm1.1Nat/Fzd7tm1.1Nat
Wnt5atm1Amc/Wnt5a+
involves: 129 * C57BL/6 		embryonic growth retardation J:189062
embryonic lethality during organogenesis, complete penetrance J:189062
Fzd2tm1.1Nat/Fzd2+
Fzd7tm1.1Nat/Fzd7tm1.1Nat
Wnt11tm1Amc/Wnt11+
involves: 129 * C57BL/6 		abnormal heart morphology J:189062
cleft palate J:189062
ventricular septal defect J:189062
Fzd2tm1.1Nat/Fzd2tm1.1Nat
Fzd7tm1.1Nat/Fzd7tm1.1Nat
involves: 129 * C57BL/6 		abnormal embryonic tissue morphology J:189062
abnormal heart development J:189062
abnormal parietal yolk sac morphology J:189062
decreased angiogenesis J:189062
decreased embryo size J:189062
disorganized yolk sac vascular plexus J:189062
embryonic growth retardation J:189062
embryonic lethality during organogenesis, complete penetrance J:189062
incomplete embryo turning J:189062
open neural tube J:189062
Fzd2tm1.1Nat/Fzd2tm1.1Nat
Vangl2Lp/Vangl2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * LPT/LeJ 		abnormal cochlear hair cell morphology J:165556
abnormal cochlear hair cell number J:165556
abnormal orientation of outer hair cell stereociliary bundles J:165556
cleft palate J:165556
open neural tube J:165556
ventricular septal defect J:165556
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory