Vav3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Vav3
vav 3 oncogene
MGI:1888518

31 phenotypes from 2 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Vav3^tm1Swat/Vav3^tm1Swat B6.129S6-Vav3^tm1Swat	normal vision/eye phenotype	J:158008
Vav3^tm1Swat/Vav3^tm1Swat involves: 129S6/SvEvTac * C57BL/6	no abnormal phenotype detected	J:86654
Vav3^tm1Xrb/Vav3^tm1Xrb Not Specified	abnormal angiogenesis	J:111973
	abnormal aorta tunica media morphology	J:111973
	abnormal blood homeostasis	J:111973
	abnormal bradykinin level	J:111973
	abnormal cardiovascular system morphology	J:111973
	abnormal cardiovascular system physiology	J:111973
	abnormal myocardial fiber morphology	J:111973
	abnormal sympathetic nervous system physiology	J:111973
	abnormal urination	J:111973
	abnormal urine homeostasis	J:111973
	cardiac fibrosis	J:111973
	decreased creatinine clearance	J:111973
	decreased heart ventricle muscle contractility	J:111973
	decreased urine potassium level	J:111973
	decreased urine sodium level	J:111973
	heart left ventricle hypertrophy	J:111973
	hypertension	J:111973
	increased angiotensin I-converting enzyme activity	J:124056
	increased circulating adrenaline level	J:111973, J:124056
	increased circulating aldosterone level	J:111973
	increased circulating angiotensin II level	J:111973
	increased circulating antidiuretic hormone level	J:111973
	increased circulating noradrenaline level	J:111973, J:124056
	increased circulating renin level	J:111973
	increased dopamine level	J:111973, J:124056
	increased heart rate	J:111973, J:124056
	increased mean systemic arterial blood pressure	J:124056
	increased renin activity	J:124056
	renal fibrosis	J:111973

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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