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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lmx1a
LIM homeobox transcription factor 1 alpha
MGI:1888519
83 phenotypes from 14 alleles in 16 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Lmx1absd/Lmx1absd
involves: 129S5/SvEvBrd 		abnormal cochlea morphology J:194385
abnormal cochlear inner hair cell morphology J:194385
abnormal inner ear vestibule morphology J:194385
abnormal placing response J:194385
abnormal utricle morphology J:194385
abnormal vestibular saccule morphology J:194385
absent pinna reflex J:194385
absent semicircular canals J:194385
belly spot J:194385
deafness J:194385
dilated endolymphatic duct J:194385
head tossing J:194385
hyperactivity J:194385
impaired righting response J:194385
increased or absent threshold for auditory brainstem response J:194385
inner ear hypoplasia J:194385
short scala media J:194385
Lmx1absd/Lmx1amtl
involves: 129S5/SvEvBrd 		belly spot J:194385
impaired hearing J:194385
increased or absent threshold for auditory brainstem response J:194385
Lmx1adr-2J/Lmx1adr-2J
involves: AKR/J 		abnormal motor coordination/balance J:14095
ataxia J:14095
belly spot J:14095
circling J:14095
deafness J:14095
head tossing J:14095
hyperactivity J:14095
impaired righting response J:14095
short tail J:14095
uterus hypoplasia J:14095
Lmx1adr-6J/Lmx1adr-6J
C3H/HeJ-Lmx1adr-6J 		ataxia J:54765
belted J:54765
circling J:54765
deafness J:54765
female infertility J:54765
hyperactivity J:54765
impaired righting response J:54765
male infertility J:54765
short tail J:54765
uterus hypoplasia J:54765
white spotting J:54765
Lmx1adr-7J/Lmx1adr-7J
B10.A-H2a H2-T18a/SgSnJ 		abnormal cerebellar foliation J:115043
abnormal cerebellum posterior vermis morphology J:115043
small cerebellum J:115043
Lmx1adr-8J/Lmx1adr-8J
B6.C3-Pde6brd1 Hps4le/J 		abnormal cerebellar foliation J:115043
abnormal cerebellum posterior vermis morphology J:115043
small cerebellum J:115043
Lmx1adr-10J/Lmx1adr-10J
129P3/J-Lmx1adr-10J/J 		abnormal cochlea morphology J:128476
abnormal cochlear labyrinth morphology J:128476
abnormal ear development J:128476
abnormal fertility/fecundity J:128476
abnormal inner ear morphology J:128476
abnormal membranous labyrinth morphology J:128476
abnormal semicircular canal morphology J:128476
absent utricle J:128476
absent vestibular saccule J:128476
bidirectional circling J:128476
decreased body size J:128476
decreased brain size J:128476
head tossing J:128476
increased or absent threshold for auditory brainstem response J:128476
kinked tail J:128476
reduced cerebellar foliation J:128476
short tail J:128476
syndromic hearing loss J:128476
Lmx1adr-11J/Lmx1adr-11J
involves: BALB/c * C57BL/6J * C57BL/Ka * NOD 		abnormal fertility/fecundity J:128476
bidirectional circling J:128476
decreased body size J:128476
head tossing J:128476
kinked tail J:128476
short tail J:128476
Lmx1adr-J/Lmx1a+
B6.Cg-Lmx1adr-J 		belly spot J:63181
Lmx1adr-J/Lmx1adr-J
B6.Cg-Lmx1adr-J 		prenatal lethality, complete penetrance J:63181
Lmx1adr-J/Lmx1adr-J
C3FeB6 A/Aw-J-Ankank Lmx1adr-J 		abnormal cerebellar foliation J:13949
abnormal righting response J:13949
belly spot J:13949
hyperactivity J:13949
infertility J:13949
preweaning lethality, incomplete penetrance J:13949
short tail J:13949
small cerebellum J:13949
Lmx1adr-J/Lmx1adr-J
involves: C3H * C57BL/6 		abnormal cell physiology J:14476
abnormal cell proliferation J:1460
abnormal cerebellar foliation J:1460
abnormal cerebellum development J:1460
abnormal cerebellum morphology J:1460
abnormal glossopharyngeal ganglion morphology J:63181
abnormal glossopharyngeal nerve morphology J:63181
abnormal hippocampus CA3 region morphology J:1460
abnormal hippocampus development J:1460
abnormal hippocampus pyramidal cell layer J:1460
abnormal interparietal bone morphology J:63181
abnormal neuronal migration J:1460
abnormal parietal bone morphology J:63181
abnormal rhombomere 3 morphology J:63181
abnormal rhombomere 4 morphology J:63181
abnormal rhombomere 5 morphology J:63181
abnormal rhombomere morphology J:63181
abnormal roof plate morphology J:63181
abnormal vertebral arch development J:63181
belly spot J:63181
circling J:63181
deafness J:63181
head tossing J:63181
postnatal lethality J:63181
spina bifida J:63181
synostosis J:63181
Lmx1adr-J/Lmx1adr-J
involves: C3HeB/Fe * C57BL/6 		abnormal cerebellum development J:152673
Lmx1adr-kjmi/Lmx1adr-kjmi
involves: 129 * C57BL/6J 		abnormal cerebellar foliation J:115043
abnormal cerebellum posterior vermis morphology J:115043
ataxia J:115043
hyperactivity J:115043
short tail J:115043
small cerebellum J:115043
white spotting J:115043
Lmx1adr-sst/Lmx1adr-sst
involves: BALB/cCf * C57BL/6J * DBA/2J 		abnormal cerebellar foliation J:12032
abnormal cerebellum development J:12032
abnormal motor coordination/balance J:12032
abnormal resting posture J:12032
abnormal tail development J:12032
bleb J:12032
deafness J:12032
hyperactivity J:12032
impaired righting response J:12032
normal mortality/aging J:12032
premature death J:12032
short tail J:12032
white spotting J:12032
Lmx1adr/Lmx1adr
Not Specified 		abnormal bony labyrinth J:14907
abnormal neural tube morphology J:13000
abnormal roof plate morphology J:13000
belted J:15346
circling J:15346
deafness J:15346
head tossing J:15346
hydrocephaly J:14907
hyperactivity J:15346
Lmx1amtl/Lmx1amtl
involves: 129S5/SvEvBrd 		abnormal cochlear inner hair cell morphology J:194385
abnormal inner ear morphology J:194385
abnormal otic vesicle development J:194385
abnormal placing response J:194385
abnormal utricle morphology J:194385
abnormal vestibular labyrinth morphology J:194385
abnormal vestibular saccule morphology J:194385
absent otoliths J:194385
absent pinna reflex J:194385
absent semicircular canals J:194385
belly spot J:194385
deafness J:194385
dilated endolymphatic duct J:194385
dilated endolymphatic sac J:194385
head tossing J:194385
hyperactivity J:194385
impaired righting response J:194385
increased or absent threshold for auditory brainstem response J:194385
short scala media J:194385
short tail J:194385
Lmx1atm1.1Tpe/Lmx1atm1.1Tpe
involves: 129S7/SvEvBrd * C57BL/6J 		decreased dopaminergic neuron number J:175535
Lmx1atm1Ics/Lmx1atm1Ics
involves: C57BL/6J 		abnormal neuron differentiation J:175535
decreased dopaminergic neuron number J:175535
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory